Next departures for Boston to Charleston on November 27
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
FlixBus + Greyhound Lines, Inc.
Bus
Boston (South Station)
4565 Gaynor Ave, North Charleston
Cheapest
Bus
Boston (South Station)
4565 Gaynor Ave, North Charleston
Fastest
FlixBus + Greyhound Lines, Inc.
Bus
Brookline
4565 Gaynor Ave, North Charleston
No tags
FlixBus + Greyhound Lines, Inc.
Bus
151 Steel Pl, Cambridge
4565 Gaynor Ave, North Charleston
No tags
Next departures for Boston to Charleston on November 28
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
FlixBus + Greyhound Lines, Inc.
Bus
Brookline
4565 Gaynor Ave, North Charleston
Cheapest
Bus
Boston (South Station)
4565 Gaynor Ave, North Charleston
Fastest
FlixBus + Greyhound Lines, Inc.
Bus
Boston (South Station)
4565 Gaynor Ave, North Charleston
No tags
FlixBus + Greyhound Lines, Inc.
Bus
Brookline
4565 Gaynor Ave, North Charleston
No tags
FlixBus + Greyhound Lines, Inc.
Bus
151 Steel Pl, Cambridge
4565 Gaynor Ave, North Charleston
No tags
Next departures for Boston to Charleston on November 29
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
FlixBus + Greyhound Lines, Inc.
Bus
151 Steel Pl, Cambridge
4565 Gaynor Ave, North Charleston
Cheapest
Bus
Boston (South Station)
4565 Gaynor Ave, North Charleston
Fastest
FlixBus + Greyhound Lines, Inc.
Bus
Boston (South Station)
4565 Gaynor Ave, North Charleston
No tags
FlixBus + Greyhound Lines, Inc.
Bus
Brookline
4565 Gaynor Ave, North Charleston
No tags
FlixBus + Greyhound Lines, Inc.
Bus
Brookline
4565 Gaynor Ave, North Charleston
No tags
Next departures for Boston to Charleston on November 30
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
FlixBus + Greyhound Lines, Inc.
Bus
Boston (South Station)
4565 Gaynor Ave, North Charleston
Cheapest
Bus
Boston (South Station)
4565 Gaynor Ave, North Charleston
Fastest
FlixBus + Greyhound Lines, Inc.
Bus
Brookline
4565 Gaynor Ave, North Charleston
No tags
FlixBus + Greyhound Lines, Inc.
Bus
Brookline
4565 Gaynor Ave, North Charleston
No tags
FlixBus + Greyhound Lines, Inc.
Bus
151 Steel Pl, Cambridge
4565 Gaynor Ave, North Charleston
No tags
Next departures for Boston to Charleston on December 1
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
FlixBus + Greyhound Lines, Inc.
Bus
Boston (South Station)
4565 Gaynor Ave, North Charleston
Cheapest
Bus
Boston (South Station)
4565 Gaynor Ave, North Charleston
Fastest
FlixBus + Greyhound Lines, Inc.
Bus
Brookline
4565 Gaynor Ave, North Charleston
No tags
FlixBus + Greyhound Lines, Inc.
Bus
Brookline
4565 Gaynor Ave, North Charleston
No tags
FlixBus + Greyhound Lines, Inc.
Bus
151 Steel Pl, Cambridge
4565 Gaynor Ave, North Charleston
No tags
Next departures for Boston to Charleston on December 2
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
FlixBus + Greyhound Lines, Inc.
Bus
151 Steel Pl, Cambridge
4565 Gaynor Ave, North Charleston
Cheapest
Bus
Boston (South Station)
4565 Gaynor Ave, North Charleston
Fastest
FlixBus + Greyhound Lines, Inc.
Bus
Boston (South Station)
4565 Gaynor Ave, North Charleston
No tags
FlixBus + Greyhound Lines, Inc.
Bus
Brookline
4565 Gaynor Ave, North Charleston
No tags
Next departures for Boston to Charleston on December 3
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
FlixBus + Greyhound Lines, Inc.
Bus
Boston (South Station)
4565 Gaynor Ave, North Charleston
Cheapest
Bus
Boston (South Station)
4565 Gaynor Ave, North Charleston
Fastest
FlixBus + Greyhound Lines, Inc.
Bus
Brookline
4565 Gaynor Ave, North Charleston
No tags
Next departures for Boston to Charleston on December 4
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
FlixBus + Greyhound Lines, Inc.
Bus
Brookline
4565 Gaynor Ave, North Charleston
Cheapest
Bus
Boston (South Station)
4565 Gaynor Ave, North Charleston
Fastest
FlixBus + Greyhound Lines, Inc.
Bus
Boston (South Station)
4565 Gaynor Ave, North Charleston
No tags
FlixBus + Greyhound Lines, Inc.
Bus
Brookline
4565 Gaynor Ave, North Charleston
No tags
Last refresh of the prices: Yesterday at 10:02 PM EST.
Compare 2 ways to go from Boston to Charleston
We recommend taking the train
Among the sustainable travel choices, the train stands out as a good way to reach Charleston. The journey takes about 19 hours 38 minutes, and with fares starting at just $187, it presents an excellent value for a comfortable ride.
Based on 87401 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the WiFi. Greyhound ticket prices on this trip start at $115
Based on 11454 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the staff but often complained with the WiFi. FlixBus ticket prices on this trip start at $360
FlixBus Boston Charleston recent customer reviews
All 3 buses were on time. Even arrived 10-15 minutes early for connections. Bus drivers were very helpful. I'm disabled & use a walker. 👍
Based on 3156 reviews, the company was rated 4 stars on Busbud. Travellers were especially satisfied with the ticket access and the staff but often complained with the WiFi. OurBus ticket prices on this trip start at $228
Frequently asked questions about travelling from Boston, MA, US to Charleston, SC, US by bus
What is the travel distance from Boston to Charleston?
The distance between Boston and Charleston is approximately 1321 km (819 miles).
What are the departure and arrival locations for buses traveling from Boston to Charleston?
Buses departing from Back Bay Station in Boston will take you to Charleston Bus Station in Charleston.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11-25
$616
11-26
$590
Today
$359
11-28
$408
11-29
$413
11-30
$434
12-01
$296
12-02
$223
The cheapest trip from Boston, MA, US to Charleston, SC, US was searched and found on Dec 2, 2025 with a price of $223
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Boston, MA, US to Charleston, SC, US, as early as possible.
You can expect to pay from $223 to $616 for a bus ticket from Boston, MA, US to Charleston, SC, US based on the last 2 days. You can expect to find the cheapest price for the trip at $223 which is on 2025-12-02.
What's the cheapest way to go from Boston, MA, US to Charleston, SC, US?
The bus is the cheapest travel choice for this destination