Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
FlixBus + Greyhound Lines, Inc. | Bus | Orlando Bus Station | 4565 Gaynor Ave, North Charleston | CheapestFastest |
Last refresh of the prices: Yesterday at 9:07 PM EST.
Compare 2 ways to go from Orlando to Charleston
Among the sustainable travel choices, the train stands out as the good way to reach Charleston. The journey takes about 7 hours 49 minutes and with fares starting at just $63, it presents an excellent value for a comfortable ride.
Where are the popular stops in Orlando and Charleston?
Stops in Orlando
- A555 N John Young Pkwy, Orlando, FL 32805
- BRedCoach Station, 1777 McCoy Road, Orlando, FL 32809
- CJet Set Express Terminal, 3718 LB Mcleod Rd., 32805 Orlando, FL,, United States
- D
Disney World
Disney's All-Star Sports Resort, 1701 West Buena Vista Dr., Orlando, FL 32830 - E
International Dr SuperTours Terminal
5419 International Dr, Orlando, FL 32819, USA - F
Seaworld Hotels
10100 International Drive , Orlando, 32821
Stops in Charleston
- A
Charleston Bus Station
3610 Dorchester Rd, North Charleston, SC 29405
Compare bus companies
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
Frequently asked questions about traveling from Orlando to Charleston, SC, US by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Orlando to Charleston?
The cheapest bus tickets from Orlando to Charleston start from $50. The average price for this route is around $65. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Orlando to Charleston?
The average bus trip duration from Orlando to Charleston is 13h 45m, covering a distance of 310 miles (500 km). The quickest bus can get you there in 7h 50m and is operated by FlixBus.
Which bus companies service the Orlando to Charleston route?
Several major train operators operate on this route with 1 trains available per day.
What is the earliest and latest departure time for the bus from Orlando to Charleston?
The earliest bus departs from Orlando to Charleston at 4:00am. And the latest bus departs at 4:45am.
What are the CO₂ emissions for the bus trip from Orlando to Charleston?
A bus trip from Orlando to Charleston generates an estimated 12 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Orlando to Charleston, SC, US was searched and found on Jan 8, 2026 with a price of $40To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Orlando to Charleston, SC, US, as early as possible.
You can expect to pay from $40 to $62 for a bus ticket from Orlando to Charleston, SC, US based on the last 2 days. You can expect to find the cheapest price for the trip at $42 which is on 2026-01-09.
What's the cheapest way to go from Orlando to Charleston, SC, US?
The Bus is the cheapest travel choice for this destination
