What is the distance between St. Louis and Cincinnati?

The distance separating St. Louis and Cincinnati is 311 miles (501 km).

What are the departure and arrival stations when taking the bus from St. Louis to Cincinnati?

If you're headed to Cincinnati from St. Louis, chances are that your bus will leave from Gateway Station and arrive at Greyhound Station. These are the main departure and arrival locations on this route, there are other pick-up and drop-off locations that could make it easier for you to reach your destination.

Bus St. Louis to Cincinnati from $41 | Refundable Tickets

Previously seen trips

Next departures for St. Louis to Cincinnati on November 26
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	2:10am	Gateway Station	14h	5:10pm	Cincinnati Bus Station	No tags
Bus	2:10am	Gateway Station	14h	5:10pm	Cincinnati Bus Station	No tags
Bus	12:50am	Gateway Station	7h 35m	9:25am	Cincinnati Bus Station	No tags
Bus	1:45pm	Gateway Station	13h 30m	4:15am	Cincinnati Bus Station	No tags
Bus	2:30am	Gateway Station	9h 10m	12:40pm	Cincinnati Bus Station	No tags

Compare 2 ways to go from St. Louis to Cincinnati

We recommend taking the bus

Among the sustainable travel choices, the bus stands out as the good way to reach Cincinnati. The journey takes about 6 hours 50 minutes and with fares starting at just $47, it presents an excellent value for a comfortable ride.

2bus per day

6h 50mAverage Duration

311 milesDistance

13kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average Price$47 - $104	Average Duration6h 50m	CO₂ emissions 13kg CO₂e
Train	Average Price$98 - $715	Average Duration18h 17m	CO₂ emissions 45kg CO₂e

Where are the popular stops in St. Louis and Cincinnati?

Stops in St. Louis

A
Gateway Station
430 S 15th St, St Louis, MO 63103
Visit page

Stops in Cincinnati

A
Greyhound Station
1005 Gilbert Ave, Cincinnati, OH 45202
Visit page
B
Northland Blvd
290-322 Northland Blvd, Springdale, OH 45246, USA

Compare bus companies

Greyhound

3.5/587,396 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

Wifi2.4

Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.

Greyhound St. Louis Cincinnati recent customer reviews

My original bus showed up 40 minutes late, so when I arrived to my transfer station the next bus had already left and I spent 8 more hours on buses than I should have.

Makayla H.

March 13, 2018

FlixBus

3.5/511,446 reviews

Staff4.2

Timeliness3.9

Cleanliness4.1

Wifi2.7

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

US bus companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Sindbad

Frequently asked questions about traveling from St. Louis to Cincinnati by bus

What is the distance between St. Louis and Cincinnati?
What are the departure and arrival stations when taking the bus from St. Louis to Cincinnati?

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

11/23

$90

11/24

$87

Today

$102

11/26

$88

11/27

$55

11/28

No data

11/29

$80

11/30

No data

The cheapest trip from St. Louis to Cincinnati was searched and found on Nov 27, 2025 with a price of $55

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from St. Louis to Cincinnati, as early as possible.

You can expect to pay from $55 to $115 for a bus ticket from St. Louis to Cincinnati based on the last 2 days. You can expect to find the cheapest price for the trip at $55 which is on 2025-11-27.