How far is South Bend from St. Louis?

The distance separating South Bend and St. Louis is 297 miles (479 km).

What are the best sights and things to do in St. Louis?

Once in St. Louis, you can start exploring the city and discover its surroundings. The top sights and things to do are Powell Symphony Hall, Forest Park, Scott Joplin House State Historic Site, Ulysses S. Grant National Historic Site and Lumière Place.

Bus South Bend to St. Louis from $59 | Refundable Tickets

Next bus departures

Next departures for South Bend to St. Louis on November 21
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended	Price and booking link
Greyhound Lines, Inc. + FlixBus	Bus	6:55pm	South Bend	12h 30m	6:25am	Gateway Station	CheapestFastest
	Bus	8:50am	South Bend	15h 35m	11:25pm	Gateway Station	No tags

Last refresh of the prices: Last Wednesday at 12:24 PM EST.

Compare 2 ways to go from South Bend to St. Louis

We recommend taking the bus

Among the sustainable travel choices, the bus stands out as the good way to reach St. Louis. The journey takes about 12 hours 30 minutes and with fares starting at just $43, it presents an excellent value for a comfortable ride.

2bus per day

12h 30mAverage Duration

296 milesDistance

12kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average Price$43 - $157	Average Duration12h 30m	CO₂ emissions 12kg CO₂e
Train	Average Price$46 - $704	Average Duration15h 32m	CO₂ emissions 43kg CO₂e

Compare bus companies

FlixBus

3.5/511,388 reviews

Staff4.2

Timeliness3.9

Cleanliness4.1

Wifi2.7

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

Greyhound

3.5/587,386 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

Wifi2.4

Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.

US bus companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Sindbad

Frequently asked questions about traveling from South Bend to St. Louis by bus

How far is South Bend from St. Louis?
What are the best sights and things to do in St. Louis?

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

11/19

$78

11/20

$55

Today

$92

11/22

$77

11/23

$89

11/24

$77

11/25

$95

11/26

$105

The cheapest trip from South Bend to St. Louis was searched and found on Nov 20, 2025 with a price of $55

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from South Bend to St. Louis, as early as possible.

You can expect to pay from $55 to $105 for a bus ticket from South Bend to St. Louis based on the last 2 days. You can expect to find the cheapest price for the trip at $77 which is on 2025-11-22.