Next departures to Chicago
One passenger / one way
- This trip is recommended because it is: Cheapest + FastestDeparture time: June 12 atDeparture city: Santa FeDeparture location: Santa Fe StationArrival time: June 13 atDestination city: ChicagoDestination location: Chicago (Union Station), ILOperated by: Amtrak
Vehicle: BusDuration: - Departure time: June 12 atDeparture city: Santa FeDeparture location: Santa Fe StationArrival time: June 13 atDestination city: ChicagoDestination location: Chicago (Union Station), ILOperated by: AmtrakVehicle: BusDuration:
- Departure time: June 12 atDeparture city: Santa FeDeparture location: Santa Fe StationArrival time: June 13 atDestination city: ChicagoDestination location: Chicago (Union Station), ILOperated by: AmtrakVehicle: BusDuration:
- Departure time: June 12 atDeparture city: Santa FeDeparture location: Santa Fe StationArrival time: June 13 atDestination city: ChicagoDestination location: Chicago (Union Station), ILOperated by: AmtrakVehicle: BusDuration:
- Departure time: June 12 atDeparture city: Santa FeDeparture location: Santa Fe StationArrival time: June 13 atDestination city: ChicagoDestination location: Chicago (Union Station), ILOperated by: AmtrakVehicle: BusDuration:
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Bus Santa Fe to Chicago: Trip Overview
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Based on 5191 reviews, the company was rated 4.1 stars on Busbud. Travelers were especially satisfied with the seats and the ticket access but often complained with the wifi. Amtrak ticket prices on this trip start at $161.00
Santa Fe to Chicago Bus
With Busbud, comparing and booking tickets for a bus from Santa Fe to Chicago is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.
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Where are the popular stops in Santa Fe and Chicago?
Frequently asked questions for your trip Santa Fe (NM), US - Chicago
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Santa Fe to Chicago was searched and found on Jun 12, 2025 with a price of $215To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Santa Fe to Chicago, as early as possible.
You can expect to pay from $215 to $2,334 for a bus ticket from Santa Fe to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at $215 which is on 2025-06-12.
About Bus Travel
Bus Travel Tips
Meet and talk to locals at the bus stations while traveling from Santa Fe to Chicago.There is no better way to get inside travel information while exploring a new city than to go straight to its people.
Start sightseeing the minute your bus leaves the station. If you're on the night bus from Santa Fe to Chicago, get comfy and count the stars.
Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Santa Fe to Chicago will emit less CO2 than a car or an airplane.
Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Santa Fe to Chicago.
Did you know?
One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.
Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travelers have used their electronic device on board during 2014.
Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!
Top traveled bus routes
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