Bus from San Antonio, US to Chicago: Tickets & Schedules
Next bus departures
Next departures for San Antonio to Chicago on November 26
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Valley Transit + Greyhound Lines, Inc. + FlixBus
Bus
San Antonio Bus Station
Chicago 95Th & Dan Ryan
Cheapest
Valley Transit + Greyhound Lines, Inc.
Bus
San Antonio Bus Station
Downtown Greyhound Station
Fastest
Bus
San Antonio Bus Station
Downtown Greyhound Station
No tags
Valley Transit + Greyhound Lines, Inc.
Bus
San Antonio Bus Station
537-517 W. Jackson Blvd
No tags
Greyhound Lines, Inc. + FlixBus
Bus
San Antonio Bus Station
Chicago 95Th & Dan Ryan
No tags
Next departures for San Antonio to Chicago on November 27
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Valley Transit + Greyhound Lines, Inc. + FlixBus
Bus
San Antonio Bus Station
Chicago 95Th & Dan Ryan
Cheapest
Conexiones + Tornado Bus
Bus
Tornado I-35
Chicago, IL
Fastest
Greyhound Lines Mexico + Greyhound Lines, Inc.
Bus
San Antonio Bus Station
Downtown Greyhound Station
No tags
FlixBus + Greyhound Lines, Inc.
Bus
San Antonio Bus Station
Downtown Greyhound Station
No tags
Valley Transit + Greyhound Lines, Inc.
Bus
San Antonio Bus Station
Downtown Greyhound Station
No tags
Next departures for San Antonio to Chicago on November 28
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Greyhound Lines Mexico + Greyhound Lines, Inc. + FlixBus
Bus
San Antonio Bus Station
Chicago 95Th & Dan Ryan
Cheapest
Conexiones + Tornado Bus
Bus
Tornado I-35
Chicago, IL
Fastest
Greyhound Lines Mexico + Greyhound Lines, Inc.
Bus
San Antonio Bus Station
Downtown Greyhound Station
No tags
FlixBus + Greyhound Lines, Inc.
Bus
San Antonio Bus Station
Downtown Greyhound Station
No tags
Valley Transit + Greyhound Lines, Inc.
Bus
San Antonio Bus Station
Downtown Greyhound Station
No tags
Next departures for San Antonio to Chicago on November 29
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Valley Transit + Greyhound Lines, Inc.
Bus
San Antonio Bus Station
Downtown Greyhound Station
Cheapest
Conexiones + Tornado Bus
Bus
Tornado I-35
Chicago, IL
Fastest
Greyhound Lines Mexico + Greyhound Lines, Inc.
Bus
San Antonio Bus Station
Downtown Greyhound Station
No tags
FlixBus + Greyhound Lines, Inc.
Bus
San Antonio Bus Station
Downtown Greyhound Station
No tags
Valley Transit + Greyhound Lines, Inc.
Bus
San Antonio Bus Station
537-517 W. Jackson Blvd
No tags
Next departures for San Antonio to Chicago on November 30
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Greyhound Lines Mexico + Greyhound Lines, Inc.
Bus
San Antonio Bus Station
Downtown Greyhound Station
Cheapest
Conexiones + Tornado Bus
Bus
Tornado I-35
Chicago, IL
Fastest
Greyhound Lines Mexico + Greyhound Lines, Inc.
Bus
San Antonio Bus Station
Downtown Greyhound Station
No tags
FlixBus + Greyhound Lines, Inc.
Bus
San Antonio Bus Station
Downtown Greyhound Station
No tags
Valley Transit + Greyhound Lines, Inc.
Bus
San Antonio Bus Station
Downtown Greyhound Station
No tags
Next departures for San Antonio to Chicago on December 1
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Greyhound Lines Mexico + Greyhound Lines, Inc.
Bus
San Antonio Bus Station
Downtown Greyhound Station
Cheapest
Conexiones + Tornado Bus
Bus
Tornado I-35
Chicago, IL
Fastest
Greyhound Lines Mexico + Greyhound Lines, Inc.
Bus
San Antonio Bus Station
Downtown Greyhound Station
No tags
FlixBus + Greyhound Lines, Inc.
Bus
Pearl District
Downtown Greyhound Station
No tags
Bus
Tornado I-35
Chicago, IL
No tags
Next departures for San Antonio to Chicago on December 2
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Greyhound Lines Mexico + Greyhound Lines, Inc.
Bus
San Antonio Bus Station
537-517 W. Jackson Blvd
Cheapest
Conexiones + Tornado Bus
Bus
Tornado I-35
Chicago, IL
Fastest
Greyhound Lines Mexico + Greyhound Lines, Inc.
Bus
San Antonio Bus Station
Downtown Greyhound Station
No tags
Bus
Tornado I-35
Chicago, IL
No tags
Greyhound Lines Mexico + Greyhound Lines, Inc.
Bus
San Antonio Bus Station
Downtown Greyhound Station
No tags
Next departures for San Antonio to Chicago on December 3
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
FlixBus + Greyhound Lines, Inc.
Bus
Pearl District
Chicago 95Th & Dan Ryan
Cheapest
Conexiones + Tornado Bus
Bus
Tornado I-35
Chicago, IL
Fastest
Greyhound Lines Mexico + Greyhound Lines, Inc.
Bus
San Antonio Bus Station
Downtown Greyhound Station
No tags
Valley Transit + Greyhound Lines, Inc.
Bus
San Antonio Bus Station
Downtown Greyhound Station
No tags
FlixBus + Greyhound Lines, Inc.
Bus
Pearl District
Downtown Greyhound Station
No tags
Last refresh of the prices: Yesterday at 7:25 PM CST.
Compare 2 ways to go from San Antonio to Chicago
We recommend taking the bus
Among the sustainable travel choices, the bus stands out as the good way to reach Chicago. The journey takes about 1 day, 6 hours 55 minutes and with fares starting at just $107, it presents an excellent value for a comfortable ride.
A Texas-based company, Tornado Bus operates throughout the United States, with routes connecting major cities, including Houston, San Antonio and El Paso. Each day,8 buses leave from their terminals to destinations across the continent. Their buses are equipped with free Wi-Fi, air conditioning, bathrooms, power outlets and a comfortable amount of legroom. With prices as low as $258 for a short ride, Tornado offers options for budget travelers, without compromising comfort. and those looking for a little luxury. The company requires printed tickets for boarding and their tickets are non-refundable, but you can exchange them up to two hours before travel time for a fee. With a friendly staff and multiple routes, traveling with Tornado is a convenient way to get around.
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Greyhound San Antonio Chicago recent customer reviews
Leaving from Memphis we back tracked to Arkansas. The bus driver kept stopping and not letting anyone know what's going on. I even asked her what was going on and why we kept stopping and she ignored me. The bus broke down 2 hrs away from Chicago. We were supposed to arrive in Chicago downtown around 6am and did not arrive until after 10am. I also paid for two seats for me and my child and he had to sit on my lap because the bus was so crowded and uncomfortable.
1 out of 5 stars
Ashley F.
The Bus was very hot the driver kepts stopping to go to the bathroom the bus broke down & finally the driver wouldnt take me to the stopping point he said that was the end of where was going. Not according to what was purchased. Had to walk rest of the way. I was not satisfied with this service at all. I am a musician performer travel all the time meet a lot of people & all my fans musician friends & relatives will be hearing about why not to book with this company. Unsatisfied Customer.
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
Based on 33 reviews, the company was rated 3 stars on Busbud. Travelers were especially satisfied with the departure location and the staff but often complained with the wifi. Valley Transit ticket prices on this trip start at $99
Frequently asked questions about traveling from San Antonio, US to Chicago by bus
What is the travel distance from San Antonio to Chicago?
The distance separating San Antonio and Chicago is 1050 miles (1693 km).
What are the departure and arrival stations when taking the bus from San Antonio to Chicago?
The majority of buses traveling from San Antonio to Chicago start their journey at Tornado I-35 and wind up at Downtown Greyhound Station. These are the main departure and arrival locations on this route, but you can find others that could fit better into your travel plans.
What are the best sights and things to do in Chicago?
Once in Chicago, you can start exploring the city and discover its surroundings. The top sights and things to do are The Field Museum, Cloud Gate, Museum of Science and Industry, Museum of Contemporary Art and Architectural River Cruise.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11/24
$265
11/25
$265
Today
$265
11/27
$253
11/28
$265
11/29
$265
11/30
$265
12/01
$265
The cheapest trip from San Antonio, US to Chicago was searched and found on Nov 27, 2025 with a price of $253
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Antonio, US to Chicago, as early as possible.
You can expect to pay from $253 to $444 for a bus ticket from San Antonio, US to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at $253 which is on 2025-11-27.
Usually Greyhound will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
The cheapest trip from San Antonio, US to Chicago was searched and found on Nov 27, 2025 with a price of $253
