Bus Tickets from San Antonio, TX to Chicago, IL

Find affordable bus tickets from San Antonio, TX to Chicago, IL with flexible options. Book your trip now

Join 75M+ travelers booking 2M+ routes across 85+ countries.
Enjoy our 24/7 customer service to assist you at every step.
Cancel anytime and receive a 100% refund, no reason needed.
TodayMay 14
from $216
TomorrowMay 15
from $207
FriMay 16
from $162
SatMay 17
SunMay 18
MonMay 19
TueMay 20
WedMay 21

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is: Cheapest
    Departure time: May 15 at
    Departure city: San Antonio
    Departure location: San Antonio Bus Station
    Arrival time: May 17 at
    Destination city: Chicago
    Destination location: Downtown Greyhound Station
    Operated by: Valley Transit Co., Inc. + Greyhound Lines, Inc.
    Valley Transit Co., Inc. + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • This trip is recommended because it is: Fastest
    Departure time: May 15 at
    Departure city: San Antonio
    Departure location: Tornado I-35
    Arrival time: May 16 at
    Destination city: Chicago
    Destination location: Chicago, IL
    Operated by: Conexiones + Tornado Bus
    Conexiones + Tornado Bus
    Vehicle: BusDuration:
  • Departure time: May 15 at
    Departure city: San Antonio
    Departure location: San Antonio Bus Station
    Arrival time: May 16 at
    Destination city: Chicago
    Destination location: Downtown Greyhound Station
    Operated by: Greyhound Lines Mexico + Greyhound Lines, Inc.
    Greyhound Lines Mexico + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: May 15 at
    Departure city: San Antonio
    Departure location: San Antonio Bus Station
    Arrival time: May 16 at
    Destination city: Chicago
    Destination location: Downtown Greyhound Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: May 15 at
    Departure city: San Antonio
    Departure location: San Antonio Bus Station
    Arrival time: May 17 at
    Destination city: Chicago
    Destination location: 537-517 W. Jackson Blvd
    Operated by: Valley Transit Co., Inc. + Greyhound Lines, Inc.
    Valley Transit Co., Inc. + Greyhound Lines, Inc.
    Vehicle: BusDuration:

Accepted payments

  • Visa
  • MasterCard
  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Compare 2 ways to go from San Antonio to Chicago.

Bus
Average Price$73 - $350Average Duration1d 6h
42kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Train
Average Price$135 - $1,176Average Duration1d 9h
154kg CO₂e1 out of 5 stars
busbud logoBusbud recommends taking the bus from San Antonio to Chicago

Among the sustainable travel choices, the bus stands out as the good way to reach Chicago. The journey takes about 1 day, 6 hours 25 minutes and with fares starting at just $73, it presents an excellent value for a comfortable ride.

18bus per day
1d 6hAverage Duration
$73Cheapest ticket
42kgCO₂ emissions

Bus San Antonio to Chicago: Trip Overview

Average ticket price$214
Average bus trip duration1d 6h
Number of daily buses18
Earliest bus departure1:30am
Distance1050 miles (1693 km)
Latest bus departure9:45pm

San Antonio to Chicago Bus

With Busbud, comparing and booking tickets for a bus from San Antonio to Chicago is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make it our job to connect you with the most dependable bus companies that cover bus service from San Antonio to Chicago.

Discover how much the bus trip from San Antonio to Chicago will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions for your trip San Antonio - Chicago

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
05/12
$222
05/13
$216
Today
$240
05/15
$240
05/16
$192
05/17
No data
05/18
$142
05/19
$145
busbud logoThe cheapest trip from San Antonio to Chicago was searched and found on May 18, 2025 with a price of $142

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Antonio to Chicago, as early as possible.

You can expect to pay from $142 to $276 for a bus ticket from San Antonio to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at $142 which is on 2025-05-18.

Usually Tornado Bus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while traveling from San Antonio to Chicago.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

From miles long of beauteous natural landscapes to impressive man-crafted sights, you're bound to be in for a visual treat on your bus trip from San Antonio to Chicago.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from San Antonio to Chicago will emit less CO2 than a car or an airplane.

Make a music playlist for your bus ride from San Antonio to Chicago, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

Will you be returning to San Antonio by bus?

Bus from San Antonio to Chicago

You can also go to Chicago by train

Train from San Antonio to Chicago

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud helps you easily search, compare and book intercity bus tickets on a worldwide scale with our comprehensive list of bus routes and schedules. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.

People from around the world trust Busbud

‌

Popular Buses Connecting San Antonio

Buses Leaving from San Antonio

Buses Going to San Antonio

Popular Buses Connecting Chicago

Buses Leaving from Chicago

Buses Going to Chicago