Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
Based on 1057 reviews, the company was rated 4.1 stars on Busbud. Travelers were especially satisfied with the departure location and the value for money but often complained with the wifi. RegioJet ticket prices on this trip start at $50
Based on 11161 reviews, the company was rated 3.7 stars on Busbud. Travelers were especially satisfied with the ticket access and the staff but often complained with the wifi. BlaBlaCar Bus ticket prices on this trip start at $345
Frequently asked questions about traveling from Prague to Rome by bus
What is the distance between Prague and Rome?
Prague and Rome are 573 miles (925 km) apart.
What are the departure and arrival stations when taking the bus from Prague to Rome?
If you're headed to Rome from Prague, chances are that your bus will depart from Černý Most and arrive at Rome Tiburtina Bus Station. These are the most popular departure and arrival locations on this route, there are other pick-up and drop-off locations that could make it easier for you to reach your destination.
What are the best sights and things to do in Rome?
Once in Rome, you can start exploring the city and discover its surroundings. The top sights and things to do are Colosseum, Piazza Navona, Cooking Classes and Food Tours in Rome, Pantheon and Teatro dell'Opera di Roma.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11/24
$76
11/25
$87
Today
$83
11/27
$85
11/28
No data
11/29
No data
11/30
No data
12/01
$67
The cheapest trip from Prague to Rome was searched and found on Dec 1, 2025 with a price of $67
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Prague to Rome, as early as possible.
You can expect to pay from $67 to $183 for a bus ticket from Prague to Rome based on the last 2 days. You can expect to find the cheapest price for the trip at $67 which is on 2025-12-01.
The cheapest trip from Prague to Rome was searched and found on Dec 1, 2025 with a price of $67
