Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | PRG Airport | Rome Tiburtina Bus Station | Cheapest | ||||
| Bus | Prague (Main Station - parking) | Rome Tiburtina Bus Station | Fastest | ||||
| Bus | Prague (Central Bus Station Florenc) | Aeroporto Ciampino Airport (CIA) | No tags | ||||
| Bus | Prague (Central Bus Station Florenc) | Aeroporto Ciampino Airport (CIA) | No tags | ||||
| Bus | Prague (Main Station - parking) | Aeroporto Ciampino Airport (CIA) | No tags |
Last refresh of the prices: Yesterday at 12:48 PM CET.
Get from Prague to Rome
The journey takes about 1 day, 20 minutes, and with fares starting at just $73, it presents an excellent value for a comfortable ride.
Where are the popular stops in Prague and Rome?
Stops in Prague
- AAviatická, 161 08, Praha 6, Czechia
- BTomíčkova 2234, Chodov, 148 00 Praha-Praha 11, Czechia
- C
Zličín
Drahoňovského, 163 00 Praha 17, Czech Republic - DChlumecká, 198 00 Praha 20, Czech Republic
- EKřižíkova 2b, Nové Město, 186 00 Praha-Praha 8, Czech Republic
- F300/8 Wilsonova, 110 00 Praha, Czechia
Stops in Rome
- ALargo Guido Mazzoni, 3, 00162 Roma, Italy
- D
Castro Pretorio
Viale Castro Pretorio 76, 00185 Roma, Italy - E
Roma
- F
Anagnina
Via Vincenzo Giudice, 00173 Roma RM, Italy
Compare bus companies
Frequently asked questions about travelling from Prague to Rome by bus
What is the distance between Prague and Rome?
The distance between Prague and Rome is approximately 925 km (573 miles).
What are the departure and arrival locations for buses traveling from Prague to Rome?
Buses departing from PRG Airport in Prague will take you to Rome Tiburtina Bus Station in Rome.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Prague to Rome was searched and found on Nov 22, 2025 with a price of $91To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Prague to Rome, as early as possible.
You can expect to pay from $91 to $349 for a bus ticket from Prague to Rome based on the last 2 days. You can expect to find the cheapest price for the trip at $96 which is on 2025-11-27.
