Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
FlixBus + Greyhound Lines, Inc. + FlixBus | Bus | Portland Curbside Bus Stop | San Ysidro Greyhound Bus Station | Cheapest | ||||
FlixBus + Greyhound Lines, Inc. | Bus | Portland Curbside Bus Stop | San Ysidro Bus terminal | Fastest | ||||
 | Bus | Portland Curbside Bus Stop | San Ysidro Bus terminal | No tags | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Portland Curbside Bus Stop | San Ysidro Greyhound Bus Station | No tags |
Last refresh of the prices: Last Tuesday at 3:23 PM PST.
Get from Portland to San Ysidro
The journey takes about 1 day, 4 hours 35 minutes and with fares starting at just $163, it presents an excellent value for a comfortable ride.
Where are the popular stops in Portland and San Ysidro?
Stops in Portland
- B7411 Northwest Station Way, Portland OR 97209, USA
- C
NW Everett & NW 8th Ave
728 NW Everett St, Portland, OR 97209, USA - D
Lloyd Center
NE 13th Ave & Holladay, Portland, OR 97232, USA - E
Pearl District
7418 NW Station Way (across street), Portland, OR 97209, USA
Compare bus companies
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Frequently asked questions about traveling from Portland, OR to San Ysidro, CA by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Portland to San Ysidro?
The cheapest bus tickets from Portland to San Ysidro start from $163. The average price for this route is around $241. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Portland to San Ysidro?
The average bus trip duration from Portland to San Ysidro is 1d 4h, covering a distance of 945 miles (1524 km). The quickest bus can get you there in 1d 10h and is operated by Greyhound.
Which bus companies service the Portland to San Ysidro route?
Several major train operators operate on this route with 1 trains available per day.
What is the earliest and latest departure time for the bus from Portland to San Ysidro?
The earliest bus departs from Portland to San Ysidro at 2:00am. And the latest bus departs at 8:00pm.
What are the CO₂ emissions for the bus trip from Portland to San Ysidro?
A bus trip from Portland to San Ysidro generates an estimated 38 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Portland, OR to San Ysidro, CA was searched and found on Dec 24, 2025 with a price of $270To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Portland, OR to San Ysidro, CA, as early as possible.
You can expect to pay from $270 to $415 for a bus ticket from Portland, OR to San Ysidro, CA based on the last 2 days. You can expect to find the cheapest price for the trip at $271 which is on 2025-12-28.
