Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
FlixBus + Greyhound Lines, Inc. + FlixBus | Bus | Portland Curbside Bus Stop | San Ysidro Greyhound Bus Station | Cheapest | ||||
FlixBus + Greyhound Lines, Inc. | Bus | Portland Curbside Bus Stop | San Ysidro Bus terminal | Fastest | ||||
 | Bus | Portland Curbside Bus Stop | San Ysidro Bus terminal | No tags | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Portland Curbside Bus Stop | San Ysidro Greyhound Bus Station | No tags |
Last refresh of the prices: Last Tuesday at 3:23 PM PST.
Get from Portland to San Ysidro
The journey takes about 1 day, 4 hours 35 minutes, and with fares starting at just $228, it presents an excellent value for a comfortable ride.
Where are the popular stops in Portland and San Ysidro?
Stops in Portland
- B7411 Northwest Station Way, Portland OR 97209, USA
- C
NW Everett & NW 8th Ave
728 NW Everett St, Portland, OR 97209, USA - D
Lloyd Center
NE 13th Ave & Holladay, Portland, OR 97232, USA - E
Pearl District
7418 NW Station Way (across street), Portland, OR 97209, USA
Compare bus companies
Based on 87452 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the WiFi. Greyhound ticket prices on this trip start at $276
Frequently asked questions about travelling from Portland, OR to San Ysidro, CA by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Portland to San Ysidro?
The cheapest bus tickets from Portland to San Ysidro start from $228. The average price for this route is around $337. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Portland to San Ysidro?
The average bus travel time from Portland to San Ysidro is 1d 4h, covering a distance of 1524 km. The quickest bus can get you there in 1d 10h and is operated by Greyhound.
Which bus companies service the Portland to San Ysidro route?
Several major bus companies operate on this route with 1 buses available per day.
What are the earliest and latest departure times for the bus from Portland to San Ysidro?
The earliest bus departs from Portland to San Ysidro at 2:00am. And the latest bus departs at 8:00pm.
What are the CO₂ emissions for the bus trip from Portland to San Ysidro?
A bus trip from Portland to San Ysidro generates an estimated 38 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Portland, OR to San Ysidro, CA was searched and found on Dec 24, 2025 with a price of $379To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Portland, OR to San Ysidro, CA, as early as possible.
You can expect to pay from $379 to $582 for a bus ticket from Portland, OR to San Ysidro, CA based on the last 2 days. You can expect to find the cheapest price for the trip at $380 which is on 2025-12-28.
