Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | TAPO | Santiago Tuxtla, Santiago Tuxtla Ver. | CheapestFastest | ||||
| Bus | TAPO | Santiago Tuxtla, Santiago Tuxtla Ver. | No tags | ||||
| Bus | TAPO | Santiago Tuxtla, Santiago Tuxtla Ver. | No tags | ||||
| Bus | Terminal del Norte | Santiago Tuxtla, Santiago Tuxtla Ver. | No tags | ||||
| Bus | Terminal del Norte | Santiago Tuxtla, Santiago Tuxtla Ver. | No tags |
Last refresh of the prices: Today at 10:55 AM CST.
Get from Mexico City to Santiago Tuxtla
The journey takes about 9 hours and with fares starting at just $76, it presents an excellent value for a comfortable ride.
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Frequently asked questions about traveling from Mexico City to Santiago Tuxtla by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Mexico City to Santiago Tuxtla?
The cheapest bus tickets from Mexico City to Santiago Tuxtla start from $76. The average price for this route is around $78. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Mexico City to Santiago Tuxtla?
The average bus trip duration from Mexico City to Santiago Tuxtla is 9h, covering a distance of 258 miles (416 km). The quickest bus can get you there in 7h 55m and is operated by ADO.
Which bus companies service the Mexico City to Santiago Tuxtla route?
Several major bus companies operate on this route with 5 buses available per day, including services from ADO, AU, Autobuses Adonai, Futura, Conexion.
What is the earliest and latest departure time for the bus from Mexico City to Santiago Tuxtla?
The earliest bus departs from Mexico City to Santiago Tuxtla at 8:00pm. And the latest bus departs at 11:59pm.
What are the CO₂ emissions for the bus trip from Mexico City to Santiago Tuxtla?
A bus trip from Mexico City to Santiago Tuxtla generates an estimated 10 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Mexico City to Santiago Tuxtla?
According to Busbud customers, the highest-rated bus company on this route is ADO, with an average rating of 4.2 out of 5 stars based on 9963 reviews.
Which bus company has the best Wi-Fi from Mexico City to Santiago Tuxtla?
Based on reviews on Busbud, the bus company ADO has the best Wi-Fi rating with a score of 2.0.
Which bus company has the most timely service from Mexico City to Santiago Tuxtla?
According to Busbud traveller reviews, the most timely bus company on this route is ADO, with a punctuality rating of 4.3 out of 5 stars.
Which bus company has the cleanest buses from Mexico City to Santiago Tuxtla?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is ADO, with a cleanliness rating of 4.7 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Mexico City to Santiago Tuxtla was searched and found on Dec 2, 2025 with a price of $70To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Mexico City to Santiago Tuxtla, as early as possible.
You can expect to pay from $70 to $71 for a bus ticket from Mexico City to Santiago Tuxtla based on the last 2 days. You can expect to find the cheapest price for the trip at $70 which is on 2025-12-02.
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