Next departures for Madrid to Santander on November 18
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Avenida de América Metro
Santander (Estacion de Autobuses)
Cheapest
Bus
Aeropuerto Adolfo Suárez Madrid-Barajas, MAD T4
Santander (Estacion de Autobuses)
Fastest
Bus
Aeropuerto Adolfo Suárez Madrid-Barajas, MAD T4
Santander (Estacion de Autobuses)
No tags
Bus
Madrid (South)
Santander (Estacion de Autobuses)
No tags
Bus
Avenida de América Metro
Santander (Estacion de Autobuses)
No tags
Next departures for Madrid to Santander on November 19
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Avenida de América Metro
Santander (Estacion de Autobuses)
Cheapest
Bus
Aeropuerto Adolfo Suárez Madrid-Barajas, MAD T4
Santander (Estacion de Autobuses)
Fastest
Bus
Avenida de América Metro
Santander (Estacion de Autobuses)
No tags
Bus
Madrid (South)
Santander (Estacion de Autobuses)
No tags
Bus
Aeropuerto Adolfo Suárez Madrid-Barajas, MAD T4
Santander (Estacion de Autobuses)
No tags
Next departures for Madrid to Santander on November 20
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Avenida de América Metro
Santander (Estacion de Autobuses)
Cheapest
Bus
Aeropuerto Adolfo Suárez Madrid-Barajas, MAD T4
Santander (Estacion de Autobuses)
Fastest
Bus
Avenida de América Metro
Santander (Estacion de Autobuses)
No tags
Bus
Madrid (South)
Santander (Estacion de Autobuses)
No tags
Bus
Aeropuerto Adolfo Suárez Madrid-Barajas, MAD T4
Santander (Estacion de Autobuses)
No tags
Next departures for Madrid to Santander on November 21
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Avenida de América Metro
Santander (Estacion de Autobuses)
Cheapest
Bus
Aeropuerto Adolfo Suárez Madrid-Barajas, MAD T4
Santander (Estacion de Autobuses)
Fastest
Bus
Avenida de América Metro
Santander (Estacion de Autobuses)
No tags
Bus
Madrid (South)
Santander (Estacion de Autobuses)
No tags
Bus
Aeropuerto Adolfo Suárez Madrid-Barajas, MAD T4
Santander (Estacion de Autobuses)
No tags
Next departures for Madrid to Santander on November 22
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Avenida de América Metro
Santander (Estacion de Autobuses)
Cheapest
Bus
Aeropuerto Adolfo Suárez Madrid-Barajas, MAD T4
Santander (Estacion de Autobuses)
Fastest
Bus
Avenida de América Metro
Santander (Estacion de Autobuses)
No tags
Bus
Madrid (South)
Santander (Estacion de Autobuses)
No tags
Bus
Aeropuerto Adolfo Suárez Madrid-Barajas, MAD T4
Santander (Estacion de Autobuses)
No tags
Next departures for Madrid to Santander on November 23
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Avenida de América Metro
Santander (Estacion de Autobuses)
Cheapest
Bus
Aeropuerto Adolfo Suárez Madrid-Barajas, MAD T4
Santander (Estacion de Autobuses)
Fastest
Bus
Avenida de América Metro
Santander (Estacion de Autobuses)
No tags
Bus
Madrid (South)
Santander (Estacion de Autobuses)
No tags
Bus
Aeropuerto Adolfo Suárez Madrid-Barajas, MAD T4
Santander (Estacion de Autobuses)
No tags
Next departures for Madrid to Santander on November 24
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Avenida de América Metro
Santander (Estacion de Autobuses)
Cheapest
Bus
Aeropuerto Adolfo Suárez Madrid-Barajas, MAD T4
Santander (Estacion de Autobuses)
Fastest
Bus
Avenida de América Metro
Santander (Estacion de Autobuses)
No tags
Bus
Madrid (South)
Santander (Estacion de Autobuses)
No tags
Bus
Aeropuerto Adolfo Suárez Madrid-Barajas, MAD T4
Santander (Estacion de Autobuses)
No tags
Next departures for Madrid to Santander on November 25
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Avenida de América Metro
Santander (Estacion de Autobuses)
Cheapest
Bus
Aeropuerto Adolfo Suárez Madrid-Barajas, MAD T4
Santander (Estacion de Autobuses)
Fastest
Bus
Avenida de América Metro
Santander (Estacion de Autobuses)
No tags
Bus
Madrid (South)
Santander (Estacion de Autobuses)
No tags
Bus
Aeropuerto Adolfo Suárez Madrid-Barajas, MAD T4
Santander (Estacion de Autobuses)
No tags
Last refresh of the prices: Today at 8:15 AM CET.
Compare 3 ways to go from Madrid to Santander
We recommend carpooling
Among the sustainable travel choices, the carpool stands out as the good way to reach Santander. The journey takes about 4 hours 20 minutes and with fares starting at just $22, it presents an excellent value for a comfortable ride.
According to 77 reviews, ALSA received a 4.3-star rating for this journey. Travelers were especially satisfied with the temperature and the departure location, but some complained about the wifi. ALSA ticket prices on this trip start at $52
ALSA Madrid Santander recent customer reviews
Alsa in general is very reliable and punctual. I have taken an Alsa bus a few times and enjoy it every time. Kudos for this company.
5 out of 5 stars
Penelope M.
Bus drivers very unfriendly, would not adjust sunscreen when sun was behind us and did not interfere with his view. Ade people run after the bus, when he knew they where running to catch up, his smile. Informed he just wanted to give them a hard time, not good pr
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
Av. de Pontejos, 33A, 39005 Santander, Cantabria, Spain
F - Estación Marítima
39002 Santander, Cantabria, Spain
Frequently asked questions about traveling from Madrid to Santander by bus
How far is Madrid from Santander?
The distance between the two cities is 211 miles (340 km).
What are the departure and arrival stations when taking the bus from Madrid to Santander?
Most of the buses traveling from Madrid to Santander leave from Madrid-Barajas Airport and arrive at Calle Navas de Tolosa, 2. These are the main departure and arrival locations on this route, but you can find others that could fit better into your travel plans.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11/16
$91
11/17
$48
Today
$48
11/19
$46
11/20
$40
11/21
$43
11/22
$40
11/23
$46
The cheapest trip from Madrid to Santander was searched and found on Nov 22, 2025 with a price of $40
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Madrid to Santander, as early as possible.
You can expect to pay from $40 to $105 for a bus ticket from Madrid to Santander based on the last 2 days. You can expect to find the cheapest price for the trip at $40 which is on 2025-11-22.
Usually FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
The cheapest trip from Madrid to Santander was searched and found on Nov 22, 2025 with a price of $40
