- Knoxville to San Antonio buses
Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
Greyhound + FlixBus | Bus | Knoxville Bus Station | Pearl District | No tags | ||||
FlixBus + Greyhound | Bus | Knoxville Bus Station | Pearl District | No tags | ||||
Greyhound + Valley Transit | Bus | Knoxville Bus Station | San Antonio Bus Station | No tags | ||||
![]() | Bus | Knoxville Bus Station | San Antonio Bus Station | No tags | ||||
Valley Transit + Greyhound | Bus | Knoxville Bus Station | San Antonio Bus Station | No tags |
Get from Knoxville to San Antonio
The journey takes about 1 day, 25 minutes and with fares starting at just $113, it presents an excellent value for a comfortable ride.
Where are the popular stops in Knoxville and San Antonio?
Stops in Knoxville
- AKnoxville Area Transit Bus Stop, 100 Kirkwood St, Knoxville, TN 37914, USA
Stops in San Antonio
- A500 N St Mary's St, San Antonio, TX 78205, USA
- B7914 Interstate 35 Access Rd, San Antonio, TX 78224, USA
- C165 Bowie St, San Antonio, 78205
- D4407 S PanAm Expy #101, San Antonio, TX 78225, USA
Compare bus companies
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Greyhound Knoxville San Antonio recent customer reviews
My bus was late showing up in Dallas my 6:30 bus either left or was late not sure but they just about didn't let me on the 8:30 bus to San Antonio
Chris R.
Frequently asked questions about traveling from Knoxville, TN to San Antonio, US by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Knoxville to San Antonio?
The cheapest bus tickets from Knoxville to San Antonio start from $113. The average price for this route is around $140. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Knoxville to San Antonio?
The average bus trip duration from Knoxville to San Antonio is 1d , covering a distance of 960 miles (1548 km). The quickest bus can get you there in 1d 3h and is operated by Greyhound.
Which bus companies service the Knoxville to San Antonio route?
Several major train operators operate on this route with 2 trains available per day.
What is the earliest and latest departure time for the bus from Knoxville to San Antonio?
The earliest bus departs from Knoxville to San Antonio at 6:10pm. And the latest bus departs at 7:05pm.
What are the CO₂ emissions for the bus trip from Knoxville to San Antonio?
A bus trip from Knoxville to San Antonio generates an estimated 39 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.






