How much is the bus ticket from Jacksonville to Louisville?

The cheapest bus tickets from Jacksonville to Louisville start from $108. The average price for this route is around $143. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

How long is the bus ride from Jacksonville to Louisville?

The average bus trip duration from Jacksonville to Louisville is 19h 10m, covering a distance of 594 miles (958 km). The quickest bus can get you there in 16h 45m and is operated by FlixBus .

Which bus companies service the Jacksonville to Louisville route?

Several major bus companies operate on this route with 6 buses available per day, including services from Greyhound , FlixBus .

What is the earliest and latest departure time for the bus from Jacksonville to Louisville?

The earliest bus departs from Jacksonville to Louisville at 8:00am. And the latest bus departs at 11:15pm.

What are the CO₂ emissions for the bus trip from Jacksonville to Louisville?

A bus trip from Jacksonville to Louisville generates an estimated 24 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.

What is the best bus company from Jacksonville to Louisville?

According to Busbud customers, the highest-rated bus company on this route is Greyhound , with an average rating of 3.5 out of 5 stars based on 87500 reviews.

Which bus company has the best Wi-Fi from Jacksonville to Louisville?

Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.

Which bus company has the most timely service from Jacksonville to Louisville?

According to Busbud traveller reviews, the most timely bus company on this route is FlixBus , with a punctuality rating of 3.9 out of 5 stars.

Which bus company has the cleanest buses from Jacksonville to Louisville?

According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus , with a cleanliness rating of 4.1 out of 5 stars.

Bus Jacksonville to Louisville from $106 | Refundable Tickets

Next bus departures

Next departures for Jacksonville to Louisville on January 17
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended	Price and booking link
FlixBus + Greyhound Lines, Inc.	Bus	9:25pm	Jacksonville Bus Station	16h 45m	2:10pm	Louisville, KY	CheapestFastest
FlixBus + Greyhound Lines, Inc.	Bus	11:15pm	Jacksonville Bus Station	1d 2h	1:30am	Louisville, KY	No tags

Next departures for Jacksonville to Louisville on January 18
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
FlixBus + Greyhound Lines, Inc.	Bus	4:30pm	Jacksonville Bus Station	17h 5m	9:35am	Louisville, KY	Cheapest
FlixBus + Greyhound Lines, Inc.	Bus	9:05am	Jacksonville Bus Station	16h 25m	1:30am	Louisville, KY	Fastest
Greyhound Lines, Inc. + FlixBus	Bus	9:30am	Jacksonville Bus Station	19h 10m	4:40am	Louisville, KY	No tags
FlixBus + Greyhound Lines, Inc.	Bus	9:25pm	Jacksonville Bus Station	16h 45m	2:10pm	Louisville, KY	No tags
FlixBus + Greyhound Lines, Inc.	Bus	11:15pm	Jacksonville Bus Station	1d 2h	1:30am	Louisville, KY	No tags

Last refresh of the prices: Yesterday at 9:21 PM EST.

Get from Jacksonville to Louisville

This route is served by bus only

The journey takes about 19 hours 10 minutes and with fares starting at just $108, it presents an excellent value for a comfortable ride.

6bus per day

19h 10mAverage Duration

594 milesDistance

24kgCO₂ emissions

Where are the popular stops in Jacksonville and Louisville?

Stops in Jacksonville

A
Jacksonville Amtrak Station
3570 Clifford Ln, Jacksonville, FL 32209, USA
Visit page Map
B
W Forsyth St
1111 W Forsyth St, Jacksonville, FL 32204, USA
Map
C
Kings Avenue Station
1003 Kings Avenue, Jacksonville, FL 32207
Map
D
JRTC Greyhound Bus Station
111 W. Forsyth St, Jacksonville, FL 32202, USA
Map

Stops in Louisville

A
Louisville Greyhound Bus Station
720 W Muhammad Ali Blvd, Louisville, KY 40203
Map

Compare bus companies

Greyhound

3.5/587,505 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

Wifi2.4

Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.

FlixBus

3.5/512,078 reviews

Staff4.1

Timeliness3.9

Cleanliness4.1

Wifi2.7

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

US bus companies:FlixBus, BlaBlaCar Bus, Greyhound, ALSA, Intercape, Trenitalia, Big Sky

Frequently asked questions about traveling from Jacksonville, FL to Louisville by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

How much is the bus ticket from Jacksonville to Louisville?
The cheapest bus tickets from Jacksonville to Louisville start from $108. The average price for this route is around $143. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Jacksonville to Louisville?
The average bus trip duration from Jacksonville to Louisville is 19h 10m, covering a distance of 594 miles (958 km). The quickest bus can get you there in 16h 45m and is operated by FlixBus.
Which bus companies service the Jacksonville to Louisville route?
Several major bus companies operate on this route with 6 buses available per day, including services from Greyhound, FlixBus.
What is the earliest and latest departure time for the bus from Jacksonville to Louisville?
The earliest bus departs from Jacksonville to Louisville at 8:00am. And the latest bus departs at 11:15pm.
What are the CO₂ emissions for the bus trip from Jacksonville to Louisville?
A bus trip from Jacksonville to Louisville generates an estimated 24 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Jacksonville to Louisville?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87500 reviews.
Which bus company has the best Wi-Fi from Jacksonville to Louisville?
Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company has the most timely service from Jacksonville to Louisville?
According to Busbud traveller reviews, the most timely bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Jacksonville to Louisville?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

01/15

No data

01/16

No data

Today

No data

01/18

No data

01/19

No data

01/20

$120

01/21

$120

01/22

No data

The cheapest trip from Jacksonville, FL to Louisville was searched and found on Jan 20, 2026 with a price of $120

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Jacksonville, FL to Louisville, as early as possible.

You can expect to pay from $120 to $120 for a bus ticket from Jacksonville, FL to Louisville based on the last 2 days. You can expect to find the cheapest price for the trip at $120 which is on 2026-01-20.