With about 2 daily trips between Ithaca and Chicago, Ourbus offers competitive fares, clean and comfortable intercity bus travel. Their buses have free WiFi, clean bathrooms, complimentary bottled water, extra legroom and power outlets. They are known for providing excellent customer service, reflecting one of the industry's highest review rates. OurBus does not charge fees to reschedule tickets, which can be changed up to 30 minutes before travel time.
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
Trailways is a network of over 70 bus companies that focus on providing quality bus rides at affordable prices all over the US since 1936. Among the most famous affiliates are Trailways of New York, Pine Hill Trailways, Adirondack Trailways and Burlington Trailways. Trailways buses have WiFi, power outlets, bathrooms, air conditioning, overhead lighting, and reclinable seats with footrests. You can find two different types of Trailway fares: saver and flexible. Saver tickets are non-refundable, while flexible tickets are fully reimbursed up to one hour before travel time. If you're traveling with them, don't forget to print your boarding pass and show a valid photo ID to board the bus.
Frequently asked questions about traveling from Ithaca, US to Chicago by bus
How far is Ithaca from Chicago?
About 572 miles (923 km) separate Ithaca and Chicago.
What are the departure and arrival stations when taking the bus from Ithaca to Chicago?
Most of the buses traveling from Ithaca to Chicago leave from Green Street and arrive at Downtown Greyhound Station. These are the main pick-up and drop-off locations on this route, but you could find others that could be a better fit for your travel plans.
What are the best sights and things to do in Chicago?
Once in Chicago, you can start exploring the city and discover its surroundings. The top sights and things to do are Chicago Shakespeare Theater on Navy Pier, Grant Park, Brookfield Zoo, Navy Pier and Robie House.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11/18
No data
11/19
No data
Today
No data
11/21
No data
11/22
No data
11/23
No data
11/24
No data
11/25
$225
The cheapest trip from Ithaca, US to Chicago was searched and found on Nov 25, 2025 with a price of $225
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Ithaca, US to Chicago, as early as possible.
You can expect to pay from $225 to $225 for a bus ticket from Ithaca, US to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at $225 which is on 2025-11-25.