What is the distance between Guadalajara and Mezcales?

The distance separating Guadalajara and Mezcales is 123 miles (197 km).

What are the departure and arrival stations when taking the bus from Guadalajara to Mezcales?

If you're headed to Mezcales from Guadalajara, chances are that your bus will leave from Nueva Central and arrive at Parada de Autobuses de Mezcales. These are the main departure and arrival locations on this route, there are other pick-up and drop-off locations that could make it easier for you to reach your destination.

Bus Guadalajara to Mezcales from $48 | Refundable Tickets

Next bus departures

Next departures for Guadalajara to Mezcales on November 26
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	12:40am	Central Camionera Poniente	3h 20m	4:00am	Nuevo Vallarta, Nayarit	CheapestFastest
Bus	5:30am	Central Camionera Poniente	3h 25m	8:55am	Nuevo Vallarta, Nayarit	No tags
Bus	10:10am	Central Camionera Poniente	3h 20m	1:30pm	Nuevo Vallarta, Nayarit	No tags
Bus	12:10pm	Central Camionera Poniente	3h 20m	3:30pm	Nuevo Vallarta, Nayarit	No tags
Bus	2:10pm	Central Camionera Poniente	3h 20m	5:30pm	Nuevo Vallarta, Nayarit	No tags

Next departures for Guadalajara to Mezcales on November 28
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	12:40am	Central Camionera Poniente	3h 20m	4:00am	Nuevo Vallarta, Nayarit	CheapestFastest
Bus	5:30am	Central Camionera Poniente	3h 25m	8:55am	Nuevo Vallarta, Nayarit	No tags
Bus	10:10am	Central Camionera Poniente	3h 20m	1:30pm	Nuevo Vallarta, Nayarit	No tags
Bus	12:10pm	Central Camionera Poniente	3h 20m	3:30pm	Nuevo Vallarta, Nayarit	No tags
Bus	2:10pm	Central Camionera Poniente	3h 20m	5:30pm	Nuevo Vallarta, Nayarit	No tags

Last refresh of the prices: Today at 9:02 AM CST.

Compare 2 ways to go from Guadalajara to Mezcales

We recommend carpooling

Among the sustainable travel choices, the carpool stands out as the good way to reach Mezcales. The journey takes about 3 hours 40 minutes and with fares starting at just $16, it presents an excellent value for a comfortable ride.

37carpool per day

3h 40mAverage Duration

121 milesDistance

8kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average Price$47 - $64	Average Duration4h 19m	CO₂ emissions 5kg CO₂e
Carpool	Average Price$16 - $25	Average Duration3h 40m	CO₂ emissions 8kg CO₂e

Where are the popular stops in Guadalajara and Mezcales?

Stops in Guadalajara

A
Nueva Central
Terminal de Autobuses de Guadalajara, Carretera Libre a Zapotlanejo y entronque carretera a Tonalá Km. 1.5, 44100 Guadalajara
Visit page
B
Guadalajara Airport
Visit page
C
Estación Juárez Parada de Autobuses
Av. Del Federalismo Nte. 800 (esq. Av. Juárez), 44100 Guadalajara, Jalisco, Mexico
Visit page
D
Central Vieja
Calle Los Ángeles 218, Las Conchas, 44460 Guadalajara, Jal., Mexico
Visit page
E
Parada de Autobuses del Mercado Del Mar en Zapopan
Prolongación Pino Suárez No. 453 (a un costado del Mercado del Mar) - El Vigìa, 45140 Zapopan
F
Santa Alicia
Plaza Santa Alicia, Avenida Guadalupe, Zapopan, Mexico

Stops in Mezcales

A
Parada de Autobuses de Mezcales
Carretera Vallarta-Tepic # 210 , Colonia Ica, Menchaca, 63150 Tepic, Nay.

Compare bus companies

Pacifico

3/5260 reviews

Staff4.1

Timeliness3

Cleanliness3.7

Wifi0.6

Futura

3.5/5736 reviews

Staff4

Timeliness2.7

Cleanliness3.9

Wifi1.7

Primera Plus

Chihuahuenses

3/5160 reviews

Staff4

Timeliness2.7

Cleanliness3.7

Wifi1.8

Nayar

2/522 reviews

Staff3.7

Timeliness3.2

Cleanliness2.3

Wifi0

Coras

Elite

2.5/5167 reviews

Staff3.3

Timeliness1.2

Cleanliness2.6

Wifi1.2

MX bus companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Sindbad

Frequently asked questions about traveling from Guadalajara, MX to Mezcales by bus

What is the distance between Guadalajara and Mezcales?
What are the departure and arrival stations when taking the bus from Guadalajara to Mezcales?

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

11/22

$48

11/23

$48

Today

$48

11/25

No data

11/26

$48

11/27

No data

11/28

$48

11/29

$49

The cheapest trip from Guadalajara, MX to Mezcales was searched and found on Nov 22, 2025 with a price of $48

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Guadalajara, MX to Mezcales, as early as possible.

You can expect to pay from $48 to $49 for a bus ticket from Guadalajara, MX to Mezcales based on the last 2 days. You can expect to find the cheapest price for the trip at $48 which is on 2025-11-28.