Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Terminal de Autobuses de Tlaquepaque | Mezcales Central Bus Station | Cheapest | ||||
 | Bus | Central Camionera Poniente | Nuevo Vallarta, Nayarit | Fastest | ||||
| Bus | Central Camionera Poniente | Nuevo Vallarta, Nayarit | No tags | ||||
 | Bus | Zapopan Guadalajara | Nogales Av. Alvaro Obregon | No tags | ||||
| Bus | Zapopan Guadalajara | Mezcales Central Bus Station | No tags |
Last refresh of the prices: Today at 2:15 PM CST.
Compare 2 ways to travel from Guadalajara to Mezcales
Among the sustainable travel choices, the carpool stands out as a good way to reach Mezcales. The journey takes about 3 hours 40 minutes and with fares starting at just R 221, it presents an excellent value for a comfortable ride.
| Average price | Average duration | CO₂ emissions | Actions | |
|---|---|---|---|---|
| Average priceR 658 - R 2 690 | Average duration4h 30m | 5kg CO₂e | ||
Carpool | Average priceR 221 - R 519 | Average duration3h 40m | 8kg CO₂e |
Where are the popular stops in Guadalajara and Mezcales?
Stops in Guadalajara
- A
Terminal de Autobuses de Tlaquepaque
Anillo Periférico Sur #8010, Col. Santa María Tequepexpan, 45601 Tlaquepaque, Jalisco - B
Estación Juárez Parada de Autobuses
Av. Del Federalismo Nte. 800 (esq. Av. Juárez), 44100 Guadalajara, Jalisco, Mexico - CTerminal de Autobuses de Guadalajara, Carretera Libre a Zapotlanejo y entronque carretera a Tonalá Km. 1.5, 44100 Guadalajara
- D
Guadalajara Airport
- E
Santa Alicia
Plaza Santa Alicia, Avenida Guadalupe, Zapopan, Mexico - F
Forum de Tlaquepaque - Parada de Autobuses
Blvd. Marcelino García Barragán No. 2077 (Col. Lomas del Paradero), 44840, Guadalajara
Stops in Mezcales
- A
Parada de Autobuses de Mezcales
Carretera Vallarta-Tepic # 210 , Colonia Ica, Menchaca, 63150 Tepic, Nay.
Compare bus companies
Frequently asked questions about travelling from Guadalajara, MX to Mezcales by bus
Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.
How much is the bus ticket from Guadalajara to Mezcales?
The cheapest bus tickets from Guadalajara to Mezcales start at R 658. The average price for this route is around R 851. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the bus journey from Guadalajara to Mezcales?
The average bus journey time from Guadalajara to Mezcales is 4h 30m, covering a distance of 201 km. The fastest bus gets you there in 3h 5m and is operated by Primera Plus.
Which bus companies service the Guadalajara to Mezcales route?
Several major bus companies operate on this route with 31 buses available per day, including services from Pacifico, Futura, Primera Plus, Chihuahuenses, Nayar, Coras, Elite.
What is the earliest and latest departure time for the bus from Guadalajara to Mezcales?
The earliest bus departs from Guadalajara to Mezcales at 00:00. And the latest bus departs at 23:59.
What are the CO₂ emissions for the bus trip from Guadalajara to Mezcales?
A bus trip from Guadalajara to Mezcales produces an estimated 5 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.
What is the best bus company from Guadalajara to Mezcales?
According to Busbud customers, the highest-rated bus company on this route is Futura, with an average rating of 3.4 out of 5 stars based on 751 reviews.
Which bus company has the best Wi-Fi from Guadalajara to Mezcales?
Based on reviews on Busbud, the bus company Primera Plus has the best Wi-Fi rating with a score of 3.0.
Which bus company offers the most punctual service from Guadalajara to Mezcales?
According to Busbud traveller reviews, the most punctual bus company on this route is Primera Plus, with a punctuality rating of 3.5 out of 5 stars.
Which bus company has the cleanest buses from Guadalajara to Mezcales?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Primera Plus, with a cleanliness rating of 5.0 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Guadalajara, MX to Mezcales was searched and found on 11 Jan 2026 with a price of R 802To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Guadalajara, MX to Mezcales as early as possible.
You can expect to pay from R 802 to R 2 687 for a bus ticket from Guadalajara, MX to Mezcales based on the last 2 days. You can expect to find the cheapest price for the trip at R 802, which is on 2026-01-11.
