Bus from Greenville, SC to Winston-Salem: Tickets & Schedules

Next bus departures

Next departures for Greenville to Winston-Salem on January 27
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound Lines, Inc.Bus
1116 Woodruff Rd
Winston Salem Greyhound Bus StationCheapest
Tornado BusBus
Greenville, (SC - Taqueria Guadalajara #3)
Winston-salem, (NC - Tienda Mexican El Crystal)Fastest
ExpresoBus
Greenville, (SC - Taqueria Guadalajara #3)
Winston-salem, (NC - Tienda Mexican El Crystal)No tags

Last refresh of the prices: Yesterday at 2:29 PM EST.

Get from Greenville to Winston-Salem

This route is served by bus only

The journey takes about 3 hours 10 minutes and with fares starting at just $34, it presents an excellent value for a comfortable ride.

3bus per day
3h 10mAverage Duration
150 milesDistance
6kgCO₂ emissions

Frequently asked questions about traveling from Greenville, SC to Winston-Salem by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

  1. How much is the bus ticket from Greenville to Winston-Salem?

    The cheapest bus tickets from Greenville to Winston-Salem start from $34. The average price for this route is around $153. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

  2. How long is the bus ride from Greenville to Winston-Salem?

    The average bus trip duration from Greenville to Winston-Salem is 3h 10m, covering a distance of 150 miles (242 km). The quickest bus can get you there in 3h 5m and is operated by Tornado Bus.

  3. Which bus companies service the Greenville to Winston-Salem route?

    Several major bus companies operate on this route with 3 buses available per day, including services from Tornado Bus, Greyhound.

  4. What is the earliest and latest departure time for the bus from Greenville to Winston-Salem?

    The earliest bus departs from Greenville to Winston-Salem at 10:50am. And the latest bus departs at 10:00pm.

  5. What are the CO₂ emissions for the bus trip from Greenville to Winston-Salem?

    A bus trip from Greenville to Winston-Salem generates an estimated 6 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.

  6. What is the best bus company from Greenville to Winston-Salem?

    According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87500 reviews.

  7. Which bus company has the best Wi-Fi from Greenville to Winston-Salem?

    Based on reviews on Busbud, the bus company Tornado Bus has the best Wi-Fi rating with a score of 4.1.

  8. Which bus company has the most timely service from Greenville to Winston-Salem?

    According to Busbud traveller reviews, the most timely bus company on this route is Tornado Bus, with a punctuality rating of 3.4 out of 5 stars.

  9. Which bus company has the cleanest buses from Greenville to Winston-Salem?

    According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Tornado Bus, with a cleanliness rating of 4.5 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
01/20
$34
01/21
$30
Today
$34
01/23
No data
01/24
No data
01/25
No data
01/26
$27
01/27
$26
busbud logoThe cheapest trip from Greenville, SC to Winston-Salem was searched and found on Jan 27, 2026 with a price of $26

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Greenville, SC to Winston-Salem, as early as possible.

You can expect to pay from $26 to $145 for a bus ticket from Greenville, SC to Winston-Salem based on the last 2 days. You can expect to find the cheapest price for the trip at $26 which is on 2026-01-27.

Usually Tornado Bus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

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