Find coaches from Greenville, SC to Winston-Salem

Find affordable coach tickets from Greenville, SC to Winston-Salem with flexible options. Book your journey now

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Today20 Jun
Tomorrow21 Jun
Sun22 Jun
from US$37
Mon23 Jun
Tue24 Jun
Wed25 Jun
from US$33
Thu26 Jun
Fri27 Jun
from US$35

Cheap buses leaving Sunday

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: 22 June at
    Departure city: Greenville
    Departure location: 1116 Woodruff Rd
    Arrival time: 22 June at
    Destination city: Winston-Salem
    Destination location: Winston Salem Greyhound Bus Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: 22 June at
    Departure city: Greenville
    Departure location: Greenville, (SC - Taqueria Guadalajara #3)
    Arrival time: 22 June at
    Destination city: Winston-Salem
    Destination location: Winston-salem, (NC - Tienda Mexican El Crystal)
    Operated by: Tornado BusTornado Bus
    Vehicle: BusDuration:
  • Departure time: 22 June at
    Departure city: Greenville
    Departure location: 1116 Woodruff Rd
    Arrival time: 22 June at
    Destination city: Winston-Salem
    Destination location: Winston Salem Greyhound Bus Station
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: 22 June at
    Departure city: Greenville
    Departure location: Greenville, (SC - Taqueria Guadalajara #3)
    Arrival time: 22 June at
    Destination city: Winston-Salem
    Destination location: Winston-salem, (NC - Tienda Mexican El Crystal)
    Operated by: Tornado BusTornado Bus
    Vehicle: BusDuration:
  • Departure time: 22 June at
    Departure city: Greenville
    Departure location: Greenville, (SC - Taqueria Guadalajara #3)
    Arrival time: 22 June at
    Destination city: Winston-Salem
    Destination location: Winston-salem, (NC - Tienda Mexican El Crystal)
    Operated by: ExpresoExpreso
    Vehicle: BusDuration:

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Compare 2 ways to travel from Greenville to Winston-Salem

Bus
Average priceUS$32 - US$158Average duration3h 10m
6kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Train
Average priceUS$59 - US$59Average duration7h 42m
22kg CO₂e1 out of 5 stars
busbud logoBusbud recommends taking the train from Greenville to Winston-Salem

Among the sustainable travel choices, the train stands out as a good way to reach Winston-Salem. The journey takes about 7 hours 42 minutes and with fares starting at just US$59, it presents an excellent value for a comfortable ride.

2train per day
7h 42mAverage duration
US$59Cheapest ticket
22kgCO₂ emissions

Bus Greenville to Winston-Salem: Trip Overview

Average ticket priceUS$137
Average bus trip duration3h 10m
Number of daily buses3.7407407407407405
Earliest bus departure10:50
Distance150 miles
Latest bus departure12:34

Greenville to Winston-Salem Bus

With Busbud, comparing and booking tickets for a bus from Greenville to Winston-Salem is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

Bus service from Greenville to Winston-Salem will be provided by the most trusted bus companies.

Discover how much the bus trip from Greenville to Winston-Salem will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip Greenville, SC - Winston-Salem

  1. What's the distance between Greenville and Winston-Salem by coach?

    The distance between Greenville and Winston-Salem by coach is approximately 149 miles (240 km).

  2. What is the best way to go from Greenville to Winston-Salem without a car?

    You can travel to Winston-Salem from Greenville by coach, which provides a smooth ride and an affordable and convenient trip. You can also consider rideshare services depending on your preferences.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
18/06
US$31
19/06
US$28
Today
US$29
21/06
No data
22/06
US$30
23/06
US$35
24/06
US$26
25/06
US$26
busbud logoThe cheapest trip from Greenville to Winston-Salem was searched and found on 24 Jun 2025 with a price of US$26

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Greenville to Winston-Salem as early as possible.

You can expect to pay from US$26 to US$130 for a bus ticket from Greenville to Winston-Salem based on the last 2 days. You can expect to find the cheapest price for the trip at US$26, which is on 2025-06-24.

Usually Expreso will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from Greenville to Winston-Salem.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Much more than a mere vehicle taking you from Greenville to Winston-Salem, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Buses have the smallest carbon footprint of all motorized transport modes. A bus going from Greenville to Winston-Salem will emit half the CO2 emitted by a train, and radically less than a car or an airplane.

Tune out to the fine sounds of your best music playlist on your bus trip from Greenville to Winston-Salem while indulging in miles on end of beautiful scenic views.

Did you know?

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

Will you be returning to Greenville by bus?

Bus from Greenville to Winston-Salem

You can also go to Winston-Salem by train

Train from Greenville to Winston-Salem

Why choose Busbud?

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Busbud.com makes it easy for you to find, compare and book city-to-city bus tickets, all over the world. We save you the extra trip to the bus station. With several language and currency options available, Busbud seeks to cater to international bus travellers no matter where they are in the world. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

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Popular Buses Connecting Greenville

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Popular Buses Connecting Winston-Salem

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