Next departures for Florence to Philadelphia on November 26
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Greyhound Lines, Inc. + FlixBus
Bus
Bus station
Philadelphia, 199 Spring Garden St
Cheapest
Greyhound Lines, Inc. + FlixBus
Bus
Bus station
199 Spring Garden St.
Fastest
Greyhound Lines, Inc. + FlixBus
Bus
Bus station
Cherry Hill Mall
No tags
Bus
Bus station
Camden (Walter Rand Transportation Center)
No tags
Greyhound Lines, Inc. + FlixBus
Bus
Bus station
Philadelphia (Logan Square)
No tags
Last refresh of the prices: Yesterday at 9:25 AM EST.
Compare 2 ways to go from Florence to Philadelphia
We recommend taking the train
Among the sustainable travel choices, the train stands out as the good way to reach Philadelphia. The journey takes about 10 hours 57 minutes and with fares starting at just $91, it presents an excellent value for a comfortable ride.
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Frequently asked questions about traveling from Florence, SC, US to Philadelphia, PA by bus
What is the distance between Florence and Philadelphia?
The distance separating Florence and Philadelphia is 467 miles (753 km).
What are the departure and arrival stations when taking the bus from Florence to Philadelphia?
If you're headed to Philadelphia from Florence, chances are that your bus will leave from Florence Bus Station and arrive at Philadelphia Airport. These are the most popular departure and arrival locations on this route, there are other pick-up and drop-off locations that could make it easier for you to reach your destination.
What are the best sights and things to do in Philadelphia?
Once in Philadelphia, you can start exploring the city and discover its surroundings. The top sights and things to do are Please Touch Museum, Arden Theatre Company, Love Park, The Franklin Institute and Betsy Ross House.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11/24
$135
11/25
$236
Today
$182
11/27
No data
11/28
$103
11/29
No data
11/30
$136
12/01
$96
The cheapest trip from Florence, SC, US to Philadelphia, PA was searched and found on Dec 1, 2025 with a price of $96
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Florence, SC, US to Philadelphia, PA, as early as possible.
You can expect to pay from $96 to $263 for a bus ticket from Florence, SC, US to Philadelphia, PA based on the last 2 days. You can expect to find the cheapest price for the trip at $96 which is on 2025-12-01.
What's the cheapest way to go from Florence, SC, US to Philadelphia, PA?
The bus is the cheapest travel choice for this destination