Bus Tickets from Detroit, MI to Winston-Salem

Next departures

Next departures for Detroit to Winston-Salem on November 3
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound Lines, Inc.
    		Detroit Bus Station
    		Winston Salem Greyhound Bus StationCheapestFastest

    Last refresh of the prices: Yesterday at 5:17 PM EST.

    Accepted payments

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    Get from Detroit to Winston-Salem

    This route is served by bus only

    The journey takes about 14 hours and with fares starting at just $74, it presents an excellent value for a comfortable ride.

    1bus per day
    14hAverage Duration
    455 milesDistance
    18kgCO₂ emissions

    Bus Detroit, MI to Winston-Salem: Trip Overview

    Average ticket price$101
    Average bus trip duration14h
    Number of daily buses1
    Earliest bus departure6:40am
    Distance456 miles (734 km)
    Latest bus departure8:15pm

    Detroit to Winston-Salem Bus

    Busbud helps you find a bus from Detroit to Winston-Salem. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

    We make sure you can find a bus service from Detroit to Winston-Salem from the most reliable bus companies operating this trip.

    Discover how much the bus trip from Detroit to Winston-Salem will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

    Frequently asked questions for your trip Detroit, MI - Winston-Salem

    Find cheapest prices for buses

    Price is for a one-way ticket for one passenger and based on past searches.

    Best price found
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    $90
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    busbud logoThe cheapest trip from Detroit, MI to Winston-Salem was searched and found on Nov 3, 2025 with a price of $90

    To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Detroit, MI to Winston-Salem, as early as possible.

    About Bus Travel

    Bus Travel Tips

    Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Detroit and Winston-Salem!

    Start sightseeing the minute your bus leaves the station. If you're on the night bus from Detroit to Winston-Salem, get comfy and count the stars.

    Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Detroit to Winston-Salem will emit less CO2 than a car or an airplane.

    Tune out to the fine sounds of your best music playlist on your bus trip from Detroit to Winston-Salem while indulging in miles on end of beautiful scenic views.

    Did you know?

    Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

    It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

    Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travelers have used their electronic device on board during 2014.

    Will you be returning to Detroit, MI by bus?

    Bus from Winston-Salem to Detroit, MI

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