Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Des Moines (Subway) | Houston Bus Station | No tags | ||||
FlixBus + Greyhound | Bus | Des Moines (Subway) | Baytown, 6800 Thompson Rd | No tags | ||||
FlixBus + Greyhound | Bus | Des Moines (Subway) | Downtown Gray & Smith | No tags | ||||
Greyhound + FlixBus | Bus | Des Moines (Subway) | Houston Uptown/Upper Kirby | No tags | ||||
| Bus | Des Moines (Subway) | Houston Bus Station | No tags |
Get from Des Moines to Houston
The journey takes about 1 day, 13 hours 55 minutes and with fares starting at just $240, it presents an excellent value for a comfortable ride.
Where are the popular stops in Des Moines and Houston?
Stops in Des Moines
- A
Jefferson/Trailways Depot
1501 2nd Ave North, Des Moines, IA 50314 - B
1514 East Grand Ave
1514 East Grand Avenue,, Des Moins, IA, 50316
Stops in Houston
- A
Hillcroft Ave & Southwest Freeway
6590 Southwest Fwy, Houston, TX 77074, USA - B2121 Main St, Houston, TX 77002
- C
Harrisburg Greyhound Station
7000 Harrisburg Blvd, Houston, TX 77011, USA - D7011 Harrisburg Blvd, Houston, TX 77011, USA
- E
Clay St & Louisiana St
600-698 Clay St, Houston, TX 77002, USA - F
Lockwood Dr & Harvey Wilson Dr
820 Lockwood Dr, Houston, TX 77002, USA
Compare bus companies
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Frequently asked questions about traveling from Des Moines to Houston, US by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Des Moines to Houston?
The cheapest bus tickets from Des Moines to Houston start from $240. The average price for this route is around $254. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Des Moines to Houston?
The average bus trip duration from Des Moines to Houston is 1d 13h, covering a distance of 826 miles (1332 km). The quickest bus can get you there in 1d 13h and is operated by Greyhound.
Which bus companies service the Des Moines to Houston route?
Several major train operators operate on this route with 1 trains available per day.
What is the earliest and latest departure time for the bus from Des Moines to Houston?
The earliest bus departs from Des Moines to Houston at 9:20am. And the latest bus departs at 9:30am.
What are the CO₂ emissions for the bus trip from Des Moines to Houston?
A bus trip from Des Moines to Houston generates an estimated 33 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Des Moines to Houston, US was searched and found on Nov 28, 2025 with a price of $264To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Des Moines to Houston, US, as early as possible.
Top traveled bus routes
People from around the world trust Busbud
Popular bus departures from Des Moines
- Find bus tickets from Des Moines to Charlotte
- Des Moines to Omaha bus times and fares
- How to travel from Des Moines to Detroit
- Find bus tickets from Des Moines to Chicago
- Des Moines to Kansas City bus times and fares
- How to travel from Des Moines to Iowa City
- Find bus tickets from Des Moines to Minneapolis