What is the distance between Colón and Santa Fe?

Colón and Santa Fe are 156 miles (251 km) apart.

What are the departure and arrival stations when taking the bus from Colón to Santa Fe?

If you're headed to Santa Fe from Colón, chances are that your bus will depart from Terminal de Omnibus Colón and arrive at Estación Terminal de Ómnibius, Santa Fe. These are the main departure and arrival locations on this route, but you can find others that could fit better into your travel plans.

What are the best sights and things to do in Santa Fe?

Once in Santa Fe, you can start exploring the city and discover its surroundings. The top sights and things to do are Santa Fe Symphony & Chorus, New Mexico State Capitol, Georgia O'Keeffe Museum, Meow Wulf’s House of Eternal Return and El Rancho de las Golondrinas.

Bus Colón to Santa Fe from $24 | Refundable Tickets

Next bus departures

Next departures for Colón to Santa Fe on November 24
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended	Price and booking link
	Bus	7:20pm	Terminal de Omnibus Colón	4h 45m	12:05am	Estación Terminal de Ómnibius, Santa Fe	CheapestFastest
	Bus	7:20pm	Terminal de Omnibus Colón	4h 45m	12:05am	Estación Terminal de Ómnibius, Santa Fe	No tags

Next departures for Colón to Santa Fe on November 25
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	3:05am	Terminal de Omnibus Colón	4h 45m	7:50am	Estación Terminal de Ómnibius, Santa Fe	CheapestFastest
Bus	3:05am	Terminal de Omnibus Colón	4h 45m	7:50am	Estación Terminal de Ómnibius, Santa Fe	No tags
Bus	7:00am	Terminal de Omnibus Colón	5h 15m	12:15pm	Estación Terminal de Ómnibius, Santa Fe	No tags
Bus	7:00am	Terminal de Omnibus Colón	5h 15m	12:15pm	Estación Terminal de Ómnibius, Santa Fe	No tags
Bus	12:20pm	Terminal de Omnibus Colón	4h 45m	5:05pm	Estación Terminal de Ómnibius, Santa Fe	No tags

Last refresh of the prices: Yesterday at 11:19 AM -03.

Get from Colón to Santa Fe

This route is served by bus only

The journey takes about 4 hours 45 minutes and with fares starting at just $21, it presents an excellent value for a comfortable ride.

3bus per day

4h 45mAverage Duration

155 milesDistance

6kgCO₂ emissions

Where are the popular stops in Colón and Santa Fe?

Stops in Colón

A
Terminal de Omnibus Colón
Sourigues 449, Colón, Entre Ríos, Argentina
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B
Colón Acceso
RN14, Entre Ríos, Argentina
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Stops in Santa Fe

A
Estación Terminal de Ómnibius, Santa Fe
Estación Terminal de Onmibus Belgrano 2900 , S3000GCH Santa Fe, Argentina
Visit page

Compare bus companies

Flechabus

4/52,116 reviews

Staff4.7

Timeliness3.4

Cleanliness4.1

Wifi1.9

Encon

4/5132 reviews

Staff4.7

Timeliness3.1

Cleanliness4.4

Wifi2.3

Nuevo Expreso

4/5299 reviews

Staff4.5

Timeliness3.3

Cleanliness4.1

Wifi1.9

Río Uruguay

Rio Uruguay

4/5572 reviews

Staff4.5

Timeliness3.7

Cleanliness4.1

Wifi0.4

AR bus companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Sindbad

Frequently asked questions about traveling from Colón, Entre Rios, AR to Santa Fe, AR by bus

What is the distance between Colón and Santa Fe?
What are the departure and arrival stations when taking the bus from Colón to Santa Fe?
What are the best sights and things to do in Santa Fe?

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

11/22

$23

11/23

No data

Today

$24

11/25

$24

11/26

No data

11/27

No data

11/28

No data

11/29

No data

The cheapest trip from Colón, Entre Rios, AR to Santa Fe, AR was searched and found on Nov 22, 2025 with a price of $23

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Colón, Entre Rios, AR to Santa Fe, AR, as early as possible.

You can expect to pay from $23 to $27 for a bus ticket from Colón, Entre Rios, AR to Santa Fe, AR based on the last 2 days. You can expect to find the cheapest price for the trip at $24 which is on 2025-11-25.