Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Terminal de Omnibus Colón | Estación Terminal de Ómnibius, Santa Fe | No tags | ||||
| Bus | Terminal de Omnibus Colón | Estación Terminal de Ómnibius, Santa Fe | No tags | ||||
| Bus | Terminal de Omnibus Colón | Estación Terminal de Ómnibius, Santa Fe | No tags | ||||
 | Bus | Terminal de Omnibus Colón | Estación Terminal de Ómnibius, Santa Fe | No tags | ||||
 | Bus | Terminal de Omnibus Colón | Estación Terminal de Ómnibius, Santa Fe | No tags |
Get from Colón to Santa Fe
The journey takes about 4 hours 45 minutes, and with fares starting at just $35, it presents an excellent value for a comfortable ride.
Where are the popular stops in Colón and Santa Fe?
Stops in Colón
- ASourigues 449, Colón, Entre Ríos, Argentina
- BRN14, Entre Ríos, Argentina
Stops in Santa Fe
- A
Estación Terminal de Ómnibius, Santa Fe
Estación Terminal de Onmibus Belgrano 2900 , S3000GCH Santa Fe, Argentina
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Frequently asked questions about travelling from Colón, Entre Rios, AR to Santa Fe, AR by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Colón to Santa Fe?
The cheapest bus tickets from Colón to Santa Fe start from $35. The average price for this route is around $37. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Colón to Santa Fe?
The average bus travel time from Colón to Santa Fe is 4h 45m, covering a distance of 250 km. The quickest bus can get you there in 4h 40m and is operated by Río Uruguay.
Which bus companies service the Colón to Santa Fe route?
Several major bus companies operate on this route with 3 buses available per day, including services from Flechabus, Encon, Nuevo Expreso, Río Uruguay, Rio Uruguay.
What are the earliest and latest departure times for the bus from Colón to Santa Fe?
The earliest bus departs from Colón to Santa Fe at 12:01am. And the latest bus departs at 8:50pm.
What are the CO₂ emissions for the bus trip from Colón to Santa Fe?
A bus trip from Colón to Santa Fe generates an estimated 6 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
What is the best bus company from Colón to Santa Fe?
According to Busbud customers, the highest-rated bus company on this route is Encon, with an average rating of 4.2 out of 5 stars based on 132 reviews.
Which bus company has the best Wi-Fi from Colón to Santa Fe?
Based on Busbud reviews, the bus company Encon has the highest Wi-Fi rating with a score of 2.3.
Which bus company has the best on-time performance from Colón to Santa Fe?
According to Busbud traveller reviews, the most punctual bus company on this route is Rio Uruguay, with a punctuality rating of 3.7 out of 5 stars.
Which bus company has the cleanest buses from Colón to Santa Fe?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Encon, with a cleanliness rating of 4.4 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Colón, Entre Rios, AR to Santa Fe, AR was searched and found on Nov 27, 2025 with a price of $33To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Colón, Entre Rios, AR to Santa Fe, AR, as early as possible.
