Bus Tickets from Charlotte, NC to Florence, SC, US
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Next departures for Charlotte to Florence on November 25
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Charlotte Bus Station
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Last refresh of the prices: Last Wednesday at 10:43 AM EST.
Compare 2 ways to go from Charlotte to Florence
We recommend taking the bus
Among the sustainable travel choices, the bus stands out as the good way to reach Florence. The journey takes about 2 hours 15 minutes and with fares starting at just $24, it presents an excellent value for a comfortable ride.
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Greyhound Charlotte Florence recent customer reviews
The bus did not arrive in Charlotte it broke down the people at Greyhound sent me on the bus all the way to Raleigh when I was just going to Florence South Carolina in Raleigh they didn't even have a bus for me to go to Florence and they wanted to send me to Fayetteville North Carolina which would have took another 6 hours and then from Fayetteville to Florence it was the worst experience I ever had
2 out of 5 stars
Robert C.
The stuff inside the station in Charlotte was horrible...poor customer service. Columbia wasn't organized, I almost missed my bus. The guy helping with bags in Columbia had good customer service. All the bus drivers were wonderful. The restroom in Charlotte is a health hazard.
Frequently asked questions about traveling from Charlotte, NC to Florence, SC, US by bus
What is the distance between Charlotte and Florence?
About 98 miles (158 km) separate Charlotte and Florence.
What are the departure and arrival stations when taking the bus from Charlotte to Florence?
If you're headed to Florence from Charlotte, chances are that your bus will leave from Tornado & El Expreso Bus Company and arrive at Florence Bus Station. These are the most popular pick-up and drop-off locations on this route, but you can also find other options that could better fit your plans.
What are the best sights and things to do in Florence?
Once in Florence, you can start exploring the city and discover its surroundings. The top sights and things to do are Santa Maria Novella, Villa Gamberaia, Palazzo Pitti, Florence Food Walking Tour and Museo degli Innocenti.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11/19
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11/20
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11/22
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11/25
$29
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The cheapest trip from Charlotte, NC to Florence, SC, US was searched and found on Nov 25, 2025 with a price of $29
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Charlotte, NC to Florence, SC, US, as early as possible.
You can expect to pay from $29 to $29 for a bus ticket from Charlotte, NC to Florence, SC, US based on the last 2 days. You can expect to find the cheapest price for the trip at $29 which is on 2025-11-25.
What's the cheapest way to go from Charlotte, NC to Florence, SC, US?
The bus is the cheapest travel choice for this destination
The cheapest trip from Charlotte, NC to Florence, SC, US was searched and found on Nov 25, 2025 with a price of $29
The bus is the cheapest travel choice for this destination
