How much is the bus ticket from Wilmington to Florence?

The cheapest bus tickets from Wilmington to Florence start at R 1 568. The average price for this route is around R 2 124. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.

How long is the bus journey from Wilmington to Florence?

The average bus journey time from Wilmington to Florence is 16h 15m, covering a distance of 721 km. The fastest bus gets you there in 12h 55m and is operated by FlixBus .

Which bus companies service the Wilmington to Florence route?

Several major bus companies operate on this route with 6 buses available per day, including services from FlixBus , Greyhound .

What is the earliest and latest departure time for the bus from Wilmington to Florence?

The earliest bus departs from Wilmington to Florence at 11:20. And the latest bus departs at 21:25.

What are the CO₂ emissions for the bus trip from Wilmington to Florence?

A bus trip from Wilmington to Florence produces an estimated 18 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.

What is the best bus company from Wilmington to Florence?

According to Busbud customers, the highest-rated bus company on this route is FlixBus , with an average rating of 3.5 out of 5 stars based on 11638 reviews.

Which bus company has the best Wi-Fi from Wilmington to Florence?

Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.

Which bus company offers the most punctual service from Wilmington to Florence?

According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus , with a punctuality rating of 3.9 out of 5 stars.

Which bus company has the cleanest buses from Wilmington to Florence?

According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus , with a cleanliness rating of 4.1 out of 5 stars.

Bus Wilmington to Florence from R 1 788 | Refundable Tickets

Next bus departures

Next departures from Wilmington to Florence on 24 December
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
FlixBus + Greyhound Lines, Inc.	Bus	19:30	Newark (DE)	16h 15m	11:45	Bus station	Cheapest
	Bus	16:50	Newark (DE)	12h 55m	05:45	Florence, SC	Fastest
Greyhound Lines, Inc. + FlixBus	Bus	21:25	Wilmington Bus Station	14h 20m	11:45	Bus station	No tags
	Bus	13:30	Delaware Rest Stop S	16h 15m	05:45	Florence, SC	No tags
Greyhound Lines, Inc. + FlixBus	Bus	13:50	Wilmington Bus Station	15h 55m	05:45	Florence, SC	No tags

Next departures from Wilmington to Florence on 25 December
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
FlixBus + Greyhound Lines, Inc.	Bus	19:30	Newark (DE)	16h 15m	11:45	Bus station	Cheapest
	Bus	16:50	Newark (DE)	12h 55m	05:45	Florence, SC	Fastest
Greyhound Lines, Inc. + FlixBus	Bus	21:25	Wilmington Bus Station	14h 20m	11:45	Bus station	No tags
	Bus	13:30	Delaware Rest Stop S	16h 15m	05:45	Florence, SC	No tags
Greyhound Lines, Inc. + FlixBus	Bus	13:50	Wilmington Bus Station	15h 55m	05:45	Florence, SC	No tags

Next departures from Wilmington to Florence on 26 December
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
FlixBus + Greyhound Lines, Inc.	Bus	19:30	Newark (DE)	16h 15m	11:45	Bus station	Cheapest
	Bus	16:50	Newark (DE)	12h 55m	05:45	Florence, SC	Fastest
Greyhound Lines, Inc. + FlixBus	Bus	21:25	Wilmington Bus Station	14h 20m	11:45	Bus station	No tags
	Bus	13:30	Delaware Rest Stop S	16h 15m	05:45	Florence, SC	No tags
Greyhound Lines, Inc. + FlixBus	Bus	13:50	Wilmington Bus Station	15h 55m	05:45	Florence, SC	No tags

Next departures from Wilmington to Florence on 27 December
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Greyhound Lines, Inc. + FlixBus	Bus	21:25	Wilmington Bus Station	14h 20m	11:45	Bus station	Cheapest
	Bus	16:50	Newark (DE)	12h 55m	05:45	Florence, SC	Fastest
Greyhound Lines, Inc. + FlixBus	Bus	13:50	Wilmington Bus Station	15h 55m	05:45	Florence, SC	No tags
	Bus	13:30	Delaware Rest Stop S	16h 15m	05:45	Florence, SC	No tags
FlixBus + Greyhound Lines, Inc.	Bus	19:30	Newark (DE)	16h 15m	11:45	Bus station	No tags

Last refresh of the prices: Yesterday at 7:24 AM EST.

Compare 2 ways to travel from Wilmington to Florence

We recommend taking the train

Among the sustainable travel choices, the train stands out as a good way to reach Florence. The journey takes about 10 hours 1 minute and with fares starting at just R 2 412, it presents an excellent value for a comfortable ride.

1train per day

10h 1mAverage duration

721 kmDistance

66kgCO₂ emissions

	Average price	Average duration	CO₂ emissions	Actions
Bus	Average priceR 1 568 - R 4 579	Average duration16h 15m	CO₂ emissions 18kg CO₂e
Train	Average priceR 2 412 - R 10 698	Average duration10h 1m	CO₂ emissions 66kg CO₂e

Where are the popular stops in Wilmington and Florence?

Stops in Wilmington

A
Wilmington Bus Station
Wilmington Bus Station, 101 N French St, Wilmington, DE 19801, USA
Visit page
B
Wilmington Station
100 French St, Wilmington, DE 19801, USA
Visit page
C
Wilmington Bus Stop
101 N French , Wilmington, DE 19801

Stops in Florence

A
Florence Bus Station
619 S Irby St, Florence, SC 29501, USA
Visit page
B
TA Travel Center - Florence
2301 W Lucas St, Florence, SC 29501, USA

Compare bus companies

FlixBus

3.5/511 711 reviews

Staff4.1

Timeliness3.9

Cleanliness4.1

WiFi2.7

Greyhound

3.5/587 448 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

WiFi2.4

US Bus Companies: FlixBus, BlaBlaCar Bus, Greyhound, ALSA, Intercape, Trenitalia, Big Sky

Frequently asked questions about travelling from Wilmington, DE to Florence, SC, US by bus

Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.

How much is the bus ticket from Wilmington to Florence?
The cheapest bus tickets from Wilmington to Florence start at R 1 568. The average price for this route is around R 2 124. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the bus journey from Wilmington to Florence?
The average bus journey time from Wilmington to Florence is 16h 15m, covering a distance of 721 km. The fastest bus gets you there in 12h 55m and is operated by FlixBus.
Which bus companies service the Wilmington to Florence route?
Several major bus companies operate on this route with 6 buses available per day, including services from FlixBus, Greyhound.
What is the earliest and latest departure time for the bus from Wilmington to Florence?
The earliest bus departs from Wilmington to Florence at 11:20. And the latest bus departs at 21:25.
What are the CO₂ emissions for the bus trip from Wilmington to Florence?
A bus trip from Wilmington to Florence produces an estimated 18 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.
What is the best bus company from Wilmington to Florence?
According to Busbud customers, the highest-rated bus company on this route is FlixBus, with an average rating of 3.5 out of 5 stars based on 11638 reviews.
Which bus company has the best Wi-Fi from Wilmington to Florence?
Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company offers the most punctual service from Wilmington to Florence?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Wilmington to Florence?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

21/12

No data

22/12

R 3 781

Today

R 3 875

24/12

R 1 788

25/12

R 2 267

26/12

R 3 362

27/12

R 2 002

28/12

No data

The cheapest trip from Wilmington, DE to Florence, SC, US was searched and found on 24 Dec 2025 with a price of R 1 788

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Wilmington, DE to Florence, SC, US as early as possible.

You can expect to pay from R 1 788 to R 3 875 for a bus ticket from Wilmington, DE to Florence, SC, US based on the last 2 days. You can expect to find the cheapest price for the trip at R 1 788, which is on 2025-12-24.