Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
FlixBus + Greyhound Lines, Inc. | Bus | San Ysidro Bus terminal | Boston (South Station) | Cheapest | ||||
FlixBus + Greyhound Lines, Inc. | Bus | San Ysidro Bus terminal | Boston (South Station) | Fastest | ||||
 | Bus | San Ysidro Bus terminal | Boston (South Station) | No tags | ||||
Greyhound Lines, Inc. + FlixBus | Bus | San Ysidro Bus terminal | Brookline | No tags | ||||
FlixBus + Greyhound Lines, Inc. | Bus | San Ysidro Bus terminal | 151 Steel Pl, Cambridge | No tags |
Last refresh of the prices: Last Wednesday at 4:02 PM PST.
Get from San Ysidro to Boston
The journey takes about 3 days, 7 hours 10 minutes, and with fares starting at just R 3 948, it presents an excellent value for a comfortable ride.
Where are the popular stops in San Ysidro and Boston?
Stops in Boston
- A145 Dartmouth St, Boston, MA 02116, USA
- B100 Legends Way, Boston, MA 02114, USA
- C
Copley Square
115-127 St James Ave, Boston, MA 02116, USA - D
Prudential MBTA Station
220 Huntington Ave, Boston, MA 02115, USA - E
Copley MBTA Station
650 Boylston St, Boston, MA 02116, USA - F
Long Wharf
66 Long Wharf, Boston, MA 02110, USA
Compare bus companies
Based on 87456 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the Wi-Fi. Greyhound ticket prices on this trip start at R 3 948
Frequently asked questions about travelling from San Ysidro, CA to Boston, MA, US by bus
Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.
How much is the bus ticket from San Ysidro to Boston?
The cheapest bus tickets from San Ysidro to Boston start at R 3 948. The average price for this route is around R 4 989. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the bus journey from San Ysidro to Boston?
The average bus journey time from San Ysidro to Boston is 3d 7h, covering a distance of 4149 km. The fastest bus gets you there in 3d 7h and is operated by Greyhound.
Which bus companies service the San Ysidro to Boston route?
Several major bus companies operate on this route with 6 buses available per day.
What is the earliest and latest departure time for the bus from San Ysidro to Boston?
The earliest bus departs from San Ysidro to Boston at 06:55. And the latest bus departs at 19:00.
What are the CO₂ emissions for the bus trip from San Ysidro to Boston?
A bus trip from San Ysidro to Boston produces an estimated 104 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from San Ysidro, CA to Boston, MA, US was searched and found on 29 Dec 2025 with a price of R 3 919To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Ysidro, CA to Boston, MA, US as early as possible.
You can expect to pay from R 3 919 to R 6 293 for a bus ticket from San Ysidro, CA to Boston, MA, US based on the last 2 days. You can expect to find the cheapest price for the trip at R 3 919, which is on 2025-12-29.
