How much is the bus ticket from San Ysidro to Boston?

The cheapest coach tickets from San Ysidro to Boston start from £176. The average price for this route is around £222. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

How long is the bus journey from San Ysidro to Boston?

The average bus journey time from San Ysidro to Boston is 3d 7h, covering a distance of 2573 miles. The fastest bus can take you there in 3d 7h and is operated by Greyhound .

Which bus companies service the San Ysidro to Boston route?

Several major bus companies operate on this route with 6 buses available per day.

What is the earliest and latest departure time for the bus from San Ysidro to Boston?

The earliest bus departs from San Ysidro to Boston at 06:55. And the latest bus departs at 19:00.

What are the CO₂ emissions for the bus trip from San Ysidro to Boston?

A bus journey from San Ysidro to Boston produces an estimated 104 kg of CO₂, making it a highly eco-friendly choice and a mode of travel recommended by Busbud.

Bus San Ysidro to Boston from £175 | Refundable Tickets

Next bus departures

Next departures from San Ysidro to Boston on 28 December
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
FlixBus + Greyhound Lines, Inc.	Bus	13:15	San Ysidro Bus terminal	3d 5h	21:50	Boston (South Station)	CheapestFastest
	Bus	19:00	San Ysidro Bus terminal	3d 7h	05:10	Boston (South Station)	No tags
Greyhound Lines, Inc. + FlixBus	Bus	19:00	San Ysidro Bus terminal	3d 11h	09:00	Brookline	No tags

Next departures from San Ysidro to Boston on 29 December
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
FlixBus + Greyhound Lines, Inc.	Bus	13:15	San Ysidro Bus terminal	3d 5h	21:45	151 Steel Pl, Cambridge	Cheapest
Greyhound Lines, Inc. + FlixBus	Bus	09:25	San Ysidro Bus terminal	3d 2h	15:10	Boston (South Station)	Fastest
FlixBus + Greyhound Lines, Inc.	Bus	13:15	San Ysidro Bus terminal	3d 5h	21:50	Boston (South Station)	No tags
	Bus	19:00	San Ysidro Bus terminal	3d 7h	05:10	Boston (South Station)	No tags
Greyhound Lines, Inc. + FlixBus	Bus	19:00	San Ysidro Bus terminal	3d 7h	05:40	Brookline	No tags

Next departures from San Ysidro to Boston on 30 December
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
FlixBus + Greyhound Lines, Inc.	Bus	13:15	San Ysidro Bus terminal	3d 5h	21:50	Boston (South Station)	Cheapest
FlixBus + Greyhound Lines, Inc.	Bus	06:55	San Ysidro Bus terminal	3d 5h	15:10	Boston (South Station)	Fastest
	Bus	19:00	San Ysidro Bus terminal	3d 7h	05:10	Boston (South Station)	No tags
Greyhound Lines, Inc. + FlixBus	Bus	19:00	San Ysidro Bus terminal	3d 7h	05:40	Brookline	No tags
FlixBus + Greyhound Lines, Inc.	Bus	06:55	San Ysidro Bus terminal	3d 9h	19:20	151 Steel Pl, Cambridge	No tags

Next departures from San Ysidro to Boston on 31 December
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
FlixBus + Greyhound Lines, Inc.	Bus	06:55	San Ysidro Bus terminal	3d 9h	19:20	151 Steel Pl, Cambridge	Cheapest
FlixBus + Greyhound Lines, Inc.	Bus	06:55	San Ysidro Bus terminal	3d 5h	15:10	Boston (South Station)	Fastest
FlixBus + Greyhound Lines, Inc.	Bus	13:15	San Ysidro Bus terminal	3d 5h	21:50	Boston (South Station)	No tags
	Bus	19:00	San Ysidro Bus terminal	3d 7h	05:10	Boston (South Station)	No tags
Greyhound Lines, Inc. + FlixBus	Bus	19:00	San Ysidro Bus terminal	3d 7h	05:40	Brookline	No tags

Next departures from San Ysidro to Boston on 1 January
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
FlixBus + Greyhound Lines, Inc.	Bus	13:15	San Ysidro Bus terminal	3d 5h	21:50	Boston (South Station)	Cheapest
Greyhound Lines, Inc. + FlixBus	Bus	09:25	San Ysidro Bus terminal	3d 2h	15:10	Boston (South Station)	Fastest
	Bus	19:00	San Ysidro Bus terminal	3d 7h	05:10	Boston (South Station)	No tags
Greyhound Lines, Inc. + FlixBus	Bus	19:00	San Ysidro Bus terminal	3d 7h	05:40	Brookline	No tags
Greyhound Lines, Inc. + FlixBus	Bus	09:25	San Ysidro Bus terminal	3d 6h	19:20	151 Steel Pl, Cambridge	No tags

Next departures from San Ysidro to Boston on 2 January
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Greyhound Lines, Inc. + FlixBus	Bus	09:25	San Ysidro Bus terminal	3d 2h	15:10	Boston (South Station)	CheapestFastest
FlixBus + Greyhound Lines, Inc.	Bus	13:15	San Ysidro Bus terminal	3d 5h	21:50	Boston (South Station)	No tags
	Bus	19:00	San Ysidro Bus terminal	3d 7h	05:10	Boston (South Station)	No tags
Greyhound Lines, Inc. + FlixBus	Bus	09:25	San Ysidro Bus terminal	3d 17h	05:40	Brookline	No tags
Greyhound Lines, Inc. + FlixBus	Bus	19:00	San Ysidro Bus terminal	3d 9h	07:20	Brookline	No tags

Last refresh of the prices: Yesterday at 13:49 PST.

Get from San Ysidro to Boston

This route is served by bus only

The journey takes about 3 days, 7 hours 10 minutes, and with fares starting at just £176, it presents an excellent value for a comfortable ride.

6bus per day

3d 7hAverage duration

2573 milesDistance

104kgCO₂ emissions

Where are the popular stops in San Ysidro and Boston?

Stops in San Ysidro

A
San Ysidro Greyhound Bus Station
731 E San Ysidro Blvd, San Ysidro, CA 92173
Visit page

Stops in Boston

A
Back Bay Station
145 Dartmouth St, Boston, MA 02116, USA
Visit page
B
North Station
100 Legends Way, Boston, MA 02114, USA
Visit page
C
Copley Square
115-127 St James Ave, Boston, MA 02116, USA
D
Prudential MBTA Station
220 Huntington Ave, Boston, MA 02115, USA
E
Copley MBTA Station
650 Boylston St, Boston, MA 02116, USA
F
Long Wharf
66 Long Wharf, Boston, MA 02110, USA

Compare bus companies

Greyhound

3.5/587,456 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

WiFi2.4

Based on 87456 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the Wi-Fi. Greyhound ticket prices on this trip start at £176

US Bus Companies: FlixBus, BlaBlaCar Bus, Greyhound, ALSA, Intercape, Trenitalia, Big Sky

Frequently asked questions about travelling by bus from San Ysidro, CA to Boston, MA, US

Please note that timetables, routes, or operator details shown here may be updated or vary at the time of your journey.

How much is the bus ticket from San Ysidro to Boston?
The cheapest coach tickets from San Ysidro to Boston start from £176. The average price for this route is around £222. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus journey from San Ysidro to Boston?
The average bus journey time from San Ysidro to Boston is 3d 7h, covering a distance of 2573 miles. The fastest bus can take you there in 3d 7h and is operated by Greyhound.
Which bus companies service the San Ysidro to Boston route?
Several major bus companies operate on this route with 6 buses available per day.
What is the earliest and latest departure time for the bus from San Ysidro to Boston?
The earliest bus departs from San Ysidro to Boston at 06:55. And the latest bus departs at 19:00.
What are the CO₂ emissions for the bus trip from San Ysidro to Boston?
A bus journey from San Ysidro to Boston produces an estimated 104 kg of CO₂, making it a highly eco-friendly choice and a mode of travel recommended by Busbud.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

26/12

£280

27/12

£214

Today

£201

29/12

£175

30/12

£198

31/12

£186

The cheapest trip from San Ysidro, CA to Boston, MA, US was searched and found on 29 Dec 2025 with a price of £175

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Ysidro, CA to Boston, MA, US as early as possible.

You can expect to pay from £175 to £280 for a bus ticket from San Ysidro, CA to Boston, MA, US based on the last 2 days. You can expect to find the cheapest price for the trip at £175, which is on 2025-12-29.