How much is the bus ticket from San Diego to Buffalo?

The cheapest bus tickets from San Diego to Buffalo start at R 3 863. The average price for this route is around R 4 720. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.

How long is the bus journey from San Diego to Buffalo?

The average bus journey time from San Diego to Buffalo is 3d 7h, covering a distance of 3528 km. The fastest bus gets you there in 2d 17h and is operated by Greyhound .

Which bus companies service the San Diego to Buffalo route?

Several major bus companies operate on this route with 11 buses available per day, including services from Greyhound , FlixBus .

What is the earliest and latest departure time for the bus from San Diego to Buffalo?

The earliest bus departs from San Diego to Buffalo at 06:45. And the latest bus departs at 19:35.

What are the CO₂ emissions for the bus trip from San Diego to Buffalo?

A bus trip from San Diego to Buffalo produces an estimated 88 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.

What is the best bus company from San Diego to Buffalo?

According to Busbud customers, the highest-rated bus company on this route is Greyhound , with an average rating of 3.5 out of 5 stars based on 87435 reviews.

Which bus company has the best Wi-Fi from San Diego to Buffalo?

Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.

Which bus company offers the most punctual service from San Diego to Buffalo?

According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus , with a punctuality rating of 3.9 out of 5 stars.

Which bus company has the cleanest buses from San Diego to Buffalo?

According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus , with a cleanliness rating of 4.1 out of 5 stars.

Bus San Diego to Buffalo from R 3 431 | Refundable Tickets

Next bus departures

Next departures from San Diego to Buffalo on 21 December
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Greyhound Lines, Inc. + FlixBus	Bus	19:35	Greyhound Bus Stop	3d 9h	07:55	Buffalo (BUF) Airport	Cheapest
	Bus	19:35	Greyhound Bus Stop	2d 17h	16:15	Niagara Frontier Transportation Authority	Fastest
FlixBus + Greyhound Lines, Inc.	Bus	15:55	San Diego (Old Town-FlixBus)	2d 21h	16:15	Niagara Frontier Transportation Authority	No tags
FlixBus + Greyhound Lines, Inc.	Bus	07:35	San Diego (Old Town-FlixBus)	3d 7h	18:30	Buffalo (BUF) Airport	No tags
FlixBus + Greyhound Lines, Inc.	Bus	12:15	San Diego (Old Town-FlixBus)	3d 13h	04:40	Buffalo (BUF) Airport	No tags

Last refresh of the prices: Yesterday at 10:22 PM PST.

Compare 2 ways to travel from San Diego to Buffalo

We recommend taking the train

Among the sustainable travel choices, the train stands out as a good way to reach Buffalo. The journey takes about 2 days, 15 hours 43 minutes and with fares starting at just R 10 488, it presents an excellent value for a comfortable ride.

2train per day

2d 15hAverage duration

3528 kmDistance

321kgCO₂ emissions

	Average price	Average duration	CO₂ emissions	Actions
Bus	Average priceR 3 863 - R 5 805	Average duration3d 7h	CO₂ emissions 88kg CO₂e
Train	Average priceR 10 488 - R 10 488	Average duration2d 15h	CO₂ emissions 321kg CO₂e

Where are the popular stops in San Diego and Buffalo?

Stops in San Diego

A
Mission Valley Sheraton
1433 Camino del Rio S, San Diego, CA 92108, USA
B
Old Town Courtyard Marriot
2435 Jefferson St, San Diego, CA 92110, USA
C
Downtown Holiday Inn
1617 1st Ave, San Diego, CA 92101, USA
D
Greyhound Station
1313 National Ave, San Diego, CA 92101, USA
E
Market St. & Park Blvd
601 Park Boulevard, San Diego, CA 92101, USA
F
San Ysidro McDonald's
727 E San Ysidro Blvd, San Diego, CA 92173, USA

Stops in Buffalo

A
Buffalo Airport
B
Transportation Center
185 Ellicott St, Buffalo, NY 14203, USA
Visit page
C
Exchange Street Station
75 Exchange St, Buffalo, NY 14203, USA
Visit page

Compare bus companies

Greyhound

3.5/587 442 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

WiFi2.4

FlixBus

3.5/511 672 reviews

Staff4.1

Timeliness3.9

Cleanliness4.1

WiFi2.7

US Bus Companies: FlixBus, BlaBlaCar Bus, Greyhound, ALSA, Intercape, Trenitalia, Big Sky

Frequently asked questions about travelling from San Diego, CA, US to Buffalo, NY by bus

Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.

How much is the bus ticket from San Diego to Buffalo?
The cheapest bus tickets from San Diego to Buffalo start at R 3 863. The average price for this route is around R 4 720. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the bus journey from San Diego to Buffalo?
The average bus journey time from San Diego to Buffalo is 3d 7h, covering a distance of 3528 km. The fastest bus gets you there in 2d 17h and is operated by Greyhound.
Which bus companies service the San Diego to Buffalo route?
Several major bus companies operate on this route with 11 buses available per day, including services from Greyhound, FlixBus.
What is the earliest and latest departure time for the bus from San Diego to Buffalo?
The earliest bus departs from San Diego to Buffalo at 06:45. And the latest bus departs at 19:35.
What are the CO₂ emissions for the bus trip from San Diego to Buffalo?
A bus trip from San Diego to Buffalo produces an estimated 88 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.
What is the best bus company from San Diego to Buffalo?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87435 reviews.
Which bus company has the best Wi-Fi from San Diego to Buffalo?
Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company offers the most punctual service from San Diego to Buffalo?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from San Diego to Buffalo?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

18/12

No data

19/12

R 4 669

Today

R 3 431

21/12

R 6 784

22/12

No data

23/12

R 4 359

24/12

No data

25/12

No data

The cheapest trip from San Diego, CA, US to Buffalo, NY was searched and found on 20 Dec 2025 with a price of R 3 431

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Diego, CA, US to Buffalo, NY as early as possible.

You can expect to pay from R 3 431 to R 6 784 for a bus ticket from San Diego, CA, US to Buffalo, NY based on the last 2 days. You can expect to find the cheapest price for the trip at R 4 359, which is on 2025-12-23.