Next departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Santa Fe Depot | Depew Station | Cheapest | |||||
| Old Town San Diego | Depew Station | Fastest | |||||
| Santa Fe Depot | Depew Station | No tags | |||||
| Old Town San Diego | Depew Station | No tags |
Last refresh of the prices: Yesterday at 10:22 PM PST.
Compare 2 ways to travel from San Diego to Buffalo
Among the sustainable travel choices, the train stands out as a good way to reach Buffalo. The journey takes about 2 days, 15 hours 43 minutes and with fares starting at just R 10 488, it presents an excellent value for a comfortable ride.
Train Companies
Based on 5662 reviews, the company was rated 4.1 stars on Busbud. Travellers were especially satisfied with the seats and the ticket access but often complained with the Wi-Fi. Amtrak ticket prices on this trip start at R 10 488
Frequently asked questions about travelling from San Diego, CA, US to Buffalo, NY by train
Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.
How much is the train ticket from San Diego to Buffalo?
The cheapest train tickets from San Diego to Buffalo start from R 10 488. The average price for this train route is around R 10 488. Busbud recommends booking your tickets in advance for a better chance to secure the lowest possible price.
How long is the train journey from San Diego to Buffalo?
The average train journey time from San Diego to Buffalo is 2d 15h, covering a distance of 3528 km. The quickest train can get you there in 2d 15h and is operated by Amtrak.
Which train operators serve the San Diego to Buffalo route?
Several major train operators run on this route, with 2 trains available per day.
What are the earliest and latest departure times for the train from San Diego to Buffalo?
The earliest train from San Diego to Buffalo departs at 14:01. And the latest train departs at 14:10.
Find cheapest prices for trains
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from San Diego, CA, US to Buffalo, NY was searched and found on 19 Dec 2025 with a price of R 9 064To save money and be sure you have the best seat, it's a good idea to buy your train tickets from San Diego, CA, US to Buffalo, NY as early as possible.
You can expect to pay from R 9 064 to R 45 714 for a train ticket from San Diego, CA, US to Buffalo, NY based on the last 2 days. You can expect to find the cheapest price for the trip at R 32 127, which is on 2025-12-21.
