How can I travel from San Diego to Buffalo without flying?

You have the option of traveling from one city to the other by either bus or train. The two options are convenient and sustainable ways to reach Buffalo. Another option is using carpool services and riding with fellow travelers.

How long does it take to get to Buffalo from San Diego by bus?

The travel time from San Diego to Buffalo is about 3d 6h, but you can get there in as little as 2d 17h with the quickest bus. This is the time it takes to travel the 2181 miles (3518 km) that separate the two cities.

What is the travel distance from San Diego to Buffalo?

About 2181 miles (3518 km) separate San Diego and Buffalo.

What are the departure and arrival stations when taking the bus from San Diego to Buffalo?

The majority of buses traveling from San Diego to Buffalo start their journey at Mission Valley Sheraton and wind up at Buffalo Airport. These are the main pick-up and drop-off locations on this route, but you can also find other options that could better fit your plans.

What is the most cost-effective way to travel from San Diego to Buffalo?

If you want the cheapest way to travel this route, take the bus. With prices starting at $214, you won't find a more affordable way to get there.

How much are the bus tickets from San Diego to Buffalo?

The average price of a one-way ticket from San Diego to Buffalo is $291. In the past 30 days, prices have fluctuated between $214 and $598, so it's best to compare them to make sure you get the best deal.

Is there an overnight bus from San Diego to Buffalo?

Yes, you can take a night bus to go from San Diego to Buffalo. Remember to bring along essentials like a blanket and some snacks to ensure a cozy and convenient journey.

San Diego (CA), US to Buffalo (NY) Bus Tickets

TodayMay 24

TomorrowMay 25

from $285

MonMay 26

from $270

TueMay 27

WedMay 28

from $235

ThuMay 29

from $251

FriMay 30

SatMay 31

Cheap buses leaving tomorrow

One passenger / one way

This trip is recommended because it is: Cheapest
Departure time: May 25 at 10:00am
Departure city: San Diego
Departure location: Greyhound Bus Stop
Arrival time: May 28 at 6:30pm
Destination city: Buffalo
Destination location: Buffalo (BUF) Airport
Operated by: Greyhound Lines, Inc. + FlixBus
Greyhound Lines, Inc. + FlixBus
Vehicle: BusDuration: 3d 5h
This trip is recommended because it is: Fastest
Departure time: May 25 at 7:35pm
Departure city: San Diego
Departure location: Greyhound Bus Stop
Arrival time: May 28 at 4:15pm
Destination city: Buffalo
Destination location: Niagara Frontier Transportation Authority
Operated by: Greyhound Lines, Inc.
Vehicle: BusDuration: 2d 17h
Departure time: May 25 at 5:00pm
Departure city: San Diego
Departure location: San Diego (Old Town-FlixBus)
Arrival time: May 28 at 4:15pm
Destination city: Buffalo
Destination location: Niagara Frontier Transportation Authority
Operated by: FlixBus + Greyhound Lines, Inc.
FlixBus + Greyhound Lines, Inc.
Vehicle: BusDuration: 2d 20h
Departure time: May 25 at 7:35pm
Departure city: San Diego
Departure location: Greyhound Bus Stop
Arrival time: May 28 at 4:15pm
Destination city: Buffalo
Destination location: Niagara Frontier Transportation Authority
Operated by: Greyhound Lines, Inc.
Vehicle: BusDuration: 2d 17h
Departure time: May 25 at 9:00am
Departure city: San Diego
Departure location: San Diego (Old Town-FlixBus)
Arrival time: May 28 at 6:30pm
Destination city: Buffalo
Destination location: Buffalo (BUF) Airport
Operated by: FlixBus + Greyhound Lines, Inc.
FlixBus + Greyhound Lines, Inc.
Vehicle: BusDuration: 3d 6h

Accepted payments

Compare 2 ways to go from San Diego to Buffalo.

	Average Price	Average Duration	CO₂ emissions
Bus	Average Price$214 - $598	Average Duration3d 6h	CO₂ emissions 88kg CO₂e5 out of 5 stars	CheapestMost eco-friendly
Train	Average Price$281 - $417	Average Duration2d 15h	CO₂ emissions 321kg CO₂e1 out of 5 stars	Fastest

Busbud recommends taking the train from San Diego to Buffalo

Among the sustainable travel choices, the train stands out as the good way to reach Buffalo. The journey takes about 2 days, 15 hours 52 minutes and with fares starting at just $281, it presents an excellent value for a comfortable ride.

4train per day

2d 15hAverage Duration

$281Cheapest ticket

321kgCO₂ emissions

Bus San Diego to Buffalo: Trip Overview

Average ticket price$291

Average bus trip duration3d 6h

Number of daily buses10

Earliest bus departure7:15am

Distance2180 miles (3515 km)

Latest bus departure7:35pm

Compare bus companies

Greyhound

3.5/586,999 reviews

Staff3.6

Timeliness2.8

Cleanliness3.3

Wifi2.3

Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.

FlixBus

3.5/58,742 reviews

Staff4.1

Timeliness4

Cleanliness4.1

Wifi2.6

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

US bus companies: FlixBus, Greyhound, Tornado Bus, Los Limousines, Valley Transit, Tufesa, Wanda Coach

San Diego to Buffalo Bus

Busbud helps you find a bus from San Diego to Buffalo. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

Bus service from San Diego to Buffalo will be provided by the most trusted bus companies.

Discover how much the bus trip from San Diego to Buffalo will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Where are the popular stops in San Diego and Buffalo?

Stops in San Diego

A - Mission Valley Sheraton

B - Old Town Courtyard Marriot

C - Downtown Holiday Inn

D - Greyhound Station

E - Market St. & Park Blvd

F - San Ysidro McDonald's

Stops in Buffalo

A - Buffalo Airport

B - Transportation Center

C - Exchange Street Station

Frequently asked questions for your trip San Diego (CA), US - Buffalo (NY)

How can I travel from San Diego to Buffalo without flying?
How long does it take to get to Buffalo from San Diego by bus?
What is the travel distance from San Diego to Buffalo?
What are the departure and arrival stations when taking the bus from San Diego to Buffalo?
What is the most cost-effective way to travel from San Diego to Buffalo?
How much are the bus tickets from San Diego to Buffalo?
Is there an overnight bus from San Diego to Buffalo?

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

05/22

No data

05/23

No data

Today

$354

05/25

$335

05/26

$293

05/27

No data

05/28

$272

05/29

$254

The cheapest trip from San Diego to Buffalo was searched and found on May 29, 2025 with a price of $254

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Diego to Buffalo, as early as possible.

You can expect to pay from $254 to $354 for a bus ticket from San Diego to Buffalo based on the last 2 days. You can expect to find the cheapest price for the trip at $254 which is on 2025-05-29.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between San Diego and Buffalo!

Much more than a mere vehicle taking you from San Diego to Buffalo, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from San Diego to Buffalo will emit less CO2 than a car or an airplane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from San Diego to Buffalo.

Did you know?

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

What's the cheapest way to go from San Diego to Buffalo?

The bus is the cheapest travel choice for this destination

Vehicle Type	Travel Time	Avg Price	Daily Departures
Vehicle TypeBus	Travel Time3d 6h	Avg Price$291	Daily Departures10
Vehicle TypeTrain	Travel Time2d 15h	Avg Price$334	Daily Departures4

Will you be returning to San Diego by bus?

Bus from San Diego to Buffalo

You can also go to Buffalo by train

Train from San Diego to Buffalo

Top traveled bus routes

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud makes bus travel easy. We help travelers find a bus, plot routes, and book intercity bus tickets all over the world. Use Busbud to book your trip online, in your own language and currency, wherever you are. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.

Bus Tickets from San Diego (CA), US to Buffalo (NY)

Cheap buses leaving tomorrow

One passenger / one way

One passenger / one way

One passenger / one way

One passenger / one way

Compare 2 ways to go from San Diego to Buffalo.

Bus San Diego to Buffalo: Trip Overview

Compare bus companies

San Diego to Buffalo Bus

Where are the popular stops in San Diego and Buffalo?

Frequently asked questions for your trip San Diego (CA), US - Buffalo (NY)

How can I travel from San Diego to Buffalo without flying?

How long does it take to get to Buffalo from San Diego by bus?

What is the travel distance from San Diego to Buffalo?

What are the departure and arrival stations when taking the bus from San Diego to Buffalo?

What is the most cost-effective way to travel from San Diego to Buffalo?

How much are the bus tickets from San Diego to Buffalo?

Is there an overnight bus from San Diego to Buffalo?

Find cheapest prices for buses

About Bus Travel

Bus Travel Tips

Did you know?

What's the cheapest way to go from San Diego to Buffalo?

Will you be returning to San Diego by bus?

You can also go to Buffalo by train

Top traveled bus routes

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

People from around the world trust Busbud

Popular Buses Connecting San Diego

Buses Leaving from San Diego

Buses Going to San Diego

Popular Buses Connecting Buffalo

Buses Leaving from Buffalo

Buses Going to Buffalo

Popular routes in this country

Popular airport transfers