Next departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Penco | Terminal Sur | Cheapest | |||||
| Penco | Terminal Sur | Fastest | |||||
| Penco | Terminal Sur | No tags | |||||
| Penco | Terminal Sur | No tags | |||||
| Penco | Terminal Sur | No tags |
Last refresh of the prices: Yesterday at 8:28 AM -03.
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Get from Penco to Santiago
The journey takes about 5 hours 6 minutes, and with fares starting at just US$15, it presents an excellent value for a comfortable ride.
Bus Penco to Santiago, CL: Trip Overview
Compare bus companies
Based on 157 reviews, the company was rated 3.8 stars on Busbud. Travellers were especially satisfied with the cleanliness and the ticket access but often complained with the Wi-Fi. Eme Bus ticket prices on this trip start at US$15
Penco to Santiago Bus
With Busbud, comparing and booking tickets for a bus from Penco to Santiago is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.
We make it our job to connect you with the most dependable bus companies that cover bus service from Penco to Santiago.
Whether it is cheap bus tickets or more luxurious buses going to Santiago from Penco, we help you find what you're looking for based on how much of a budget you have.
Where are the popular stops in Penco and Santiago?
Frequently asked questions on the trip Penco - Santiago, CL
How much does a bus ticket from Penco to Santiago cost?
The bus ticket price from Penco to Santiago starts at US$15. The best way to find cheap bus tickets from Penco to Santiago is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!
How long is the bus ride from Penco to Santiago?
The average travel time between Penco and Santiago is around 5h 6m, although the fastest bus will take about 5h 5m. This is the time it takes to travel the 429 km that separates the two cities.
How many daily bus connections are there between Penco and Santiago?
The number of buses from Penco to Santiago can differ depending on the day of the week. On average, there are 9 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Penco to Santiago by comparing and selecting the bus that fits your travel style and budget on Busbud.
Which bus companies travel from Penco to Santiago?
When taking the bus from Penco to Santiago, you can travel comfortably and safely with Eme Bus.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Penco to Santiago, CL was searched and found on 03 Nov 2025 with a price of US$20To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Penco to Santiago, CL as early as possible.
About Bus Travel
Bus Travel Tips
Meet and talk to locals at the bus stations while travelling from Penco to Santiago.There is no better way to get inside travel information while exploring a new city than to go straight to its people.
From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Penco to Santiago.
Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Penco to Santiago.
Make a music playlist for your bus ride from Penco to Santiago, and enjoy the scenery to tunes from your own personal soundtrack.
Did you know?
One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.
The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.
9.2% of ground transportation in Europe is done by bus versus 7.4% by train.
Top travelled bus routes
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Popular Buses Connecting Penco
Buses Leaving from Penco
Buses Going to Penco
Popular Buses Connecting Santiago
Buses Leaving from Santiago
- Bus from Santiago to Puerto Montt
- Coach Santiago - Concepción
- Bus Santiago - Antofagasta
- Bus from Santiago to Mendoza
- Coach Santiago - La Serena
- Bus Santiago - Temuco
- Bus from Santiago to Los Alamos
- Coach Santiago - La Boca
- Bus Santiago - Licanray
- Bus from Santiago to Laraquete
- Coach Santiago - Carahue
- Bus Santiago - Quintero
- Bus from Santiago to Valparaiso
- Coach Santiago - Cholchol
- Bus Santiago - Coronel
Buses Going to Santiago
- Bus from Victoria to Santiago
- Coach Concepción - Santiago
- Bus Mendoza - Santiago
- Bus from Castro to Santiago
- Coach Valdivia - Santiago
- Bus Antofagasta - Santiago
- Bus from Labranza to Santiago
- Coach Pupuya - Santiago
- Bus La Boca - Santiago
- Bus from Alto Hospicio to Santiago
- Coach Vicuña - Santiago
- Bus Matanzas - Santiago
- Bus from Los Lagos to Santiago
- Coach Casablanca - Santiago
- Bus Purén - Santiago