How far is Penco from Santiago?

Penco and Santiago are 266 miles (429 km) apart.

What are the departure and arrival stations when taking the bus from Penco to Santiago?

Most of the buses traveling from Penco to Santiago leave from Terminal de Autobuses de Penco and arrive at Terminal Sur. These are the primary departure and arrival locations on this route, but you can find others that could fit better into your travel plans.

What are the best sights and things to do in Santiago?

Once in Santiago, you can start exploring the city and discover its surroundings. The top sights and things to do are Museo Nacional de Bellas Artes, La Chascona House, Museo Chileno de Arte Precolombino, Casablanca Valley Wine Tasting and El Biógrafo.

Bus Penco to Santiago from $13 | Refundable Tickets

Next bus departures

Next departures for Penco to Santiago on November 30
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	12:50pm	Penco	5h 6m	5:56pm	Terminal Sur	Cheapest
Bus	12:50pm	Penco	5h 6m	5:56pm	Terminal Sur	Fastest
Bus	11:05pm	Penco	5h 6m	4:11am	Terminal Sur	No tags
Bus	11:25pm	Penco	5h 6m	4:31am	Terminal Sur	No tags
Bus	11:05am	Penco	5h 6m	4:11pm	Terminal Sur	No tags

Last refresh of the prices: Last Sunday at 9:03 AM -03.

Get from Penco to Santiago

This route is served by bus only

The journey takes about 5 hours 6 minutes and with fares starting at just $15, it presents an excellent value for a comfortable ride.

10bus per day

5h 6mAverage Duration

261 milesDistance

11kgCO₂ emissions

Where are the popular stops in Penco and Santiago?

Stops in Penco

A
Terminal de Autobuses de Penco
Ruta 150 9, Penco, Región del Bío Bío, Chile

Stops in Santiago

A
Terminal Sur
Santiago - Av Libertador Bernardo O'Higgins 3850, Santiago, Estación Central, Región Metropolitana, Chile
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B
San Borja
San Francisco de Borja 199-225, Santiago, Estación Central, Región Metropolitana, Chile
C
Terminal Los Héroes
Tucapel Jiménez 21, 8340528 Santiago, Región Metropolitana, Chile
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D
Terminal ETM
Pdte. Riesco 6391-6399, Las Condes, Región Metropolitana, Chile
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E
Pajaritos
Av. Gral. Oscar Bonilla 418, Lo Prado, Región Metropolitana, Chile
Visit page
F
Santiago
Juan Esteban Montero 5688, Las Condes, Las Condes, Región Metropolitana, Chile

Compare bus companies

Eme Bus

4/5157 reviews

Staff4.6

Timeliness4.4

Cleanliness4.8

Wifi2.9

Based on 157 reviews, the company was rated 3.8 stars on Busbud. Travelers were especially satisfied with the cleanliness and the ticket access but often complained with the wifi. Eme Bus ticket prices on this trip start at $15

CL bus companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Sindbad

Frequently asked questions about traveling from Penco to Santiago, CL by bus

How far is Penco from Santiago?
What are the departure and arrival stations when taking the bus from Penco to Santiago?
What are the best sights and things to do in Santiago?

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

11/24

No data

11/25

No data

Today

No data

11/27

No data

11/28

$14

11/29

$14

11/30

$14

12/01

No data

The cheapest trip from Penco to Santiago, CL was searched and found on Nov 28, 2025 with a price of $14

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Penco to Santiago, CL, as early as possible.

You can expect to pay from $14 to $26 for a bus ticket from Penco to Santiago, CL based on the last 2 days. You can expect to find the cheapest price for the trip at $14 which is on 2025-11-28.