Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Orlando Bus Station | Bus station | Cheapest | ||||
| Bus | Orlando Bus Station | Florence, SC | Fastest | ||||
| Bus | Orlando Bus Station | Bus station | No tags | ||||
| Bus | The Florida Mall | Florence, SC | No tags |
Last refresh of the prices: Today at 8:00 AM EST.
Compare 2 ways to travel from Orlando to Florence
Among the sustainable travel choices, the bus stands out as a good way to reach Florence. The journey takes about 9 hours 35 minutes and with fares starting at just R 1 008, it presents an excellent value for a comfortable ride.
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Where are the popular stops in Orlando and Florence?
Frequently asked questions about travelling from Orlando to Florence, SC, US by bus
How much does a bus ticket from Orlando to Florence cost?
The bus ticket price from Orlando to Florence starts at R 1 008. The best way to find cheap bus tickets from Orlando to Florence is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!
How long is the bus ride from Orlando to Florence?
The average travel time between Orlando and Florence is around 9h 35m, although the fastest bus will take about 8h 25m. This is the time it takes to travel the 653 km that separates the two cities.
How many daily bus connections are there between Orlando and Florence?
The number of buses from Orlando to Florence can differ depending on the day of the week. On average, there are 3 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Orlando to Florence by comparing and selecting the bus that fits your travel style and budget on Busbud.
Which bus companies travel from Orlando to Florence?
When taking the bus from Orlando to Florence, you can travel comfortably and safely with FlixBus, Greyhound.
What are the departure and arrival stations when taking the bus from Orlando to Florence?
Buses travelling between Orlando and Florence leave from Orlando Bus Station or Orlando RedCoach Station and arrive at Florence Bus Station, TA Travel Center - Florence.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Orlando to Florence, SC, US was searched and found on 17 Nov 2025 with a price of R 1 480To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Orlando to Florence, SC, US as early as possible.
You can expect to pay from R 1 480 to R 2 996 for a bus ticket from Orlando to Florence, SC, US based on the last 2 days. You can expect to find the cheapest price for the trip at R 1 480, which is on 2025-11-24.
What's the cheapest way to go from Orlando to Florence, SC, US?
The bus is the cheapest travel choice for this destination
