Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Heinrich-von-Stephan-Straße 4-6 | Prague (Central Bus Station Florenc) | Cheapest | ||||
| Bus | Heinrich-von-Stephan-Straße 4-6 | Prague (Na Knížecí) | Fastest | ||||
| Bus | Heinrich-von-Stephan-Straße 4-6 | Prague (Central Bus Station Florenc) | No tags | ||||
| Bus | Heinrich-von-Stephan-Straße 4-6 | Prague (Central Bus Station Florenc) | No tags | ||||
| Bus | Heinrich-von-Stephan-Straße 4-6 | Prague (Na Knížecí) | No tags |
Last refresh of the prices: Last Saturday at 9:41 AM CET.
Compare 3 ways to travel from Mannheim to Prague
Among the sustainable travel choices, the carpool stands out as a good way to reach Prague. The journey takes about 5 hours 10 minutes and with fares starting at just R 495, it presents an excellent value for a comfortable ride.
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Where are the popular stops in Mannheim and Prague?
Frequently asked questions about travelling from Mannheim to Prague by bus
How much does a bus ticket from Mannheim to Prague cost?
The bus ticket price from Mannheim to Prague starts at R 711. The best way to find cheap bus tickets from Mannheim to Prague is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!
How long is the bus ride from Mannheim to Prague?
The average travel time between Mannheim and Prague is around 7h 35m, although the fastest bus will take about 6h 40m. This is the time it takes to travel the 432 km that separates the two cities.
How many daily bus connections are there between Mannheim and Prague?
The number of buses from Mannheim to Prague can differ depending on the day of the week. On average, there are 6 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Mannheim to Prague by comparing and selecting the bus that fits your travel style and budget on Busbud.
Which bus companies travel from Mannheim to Prague?
When taking the bus from Mannheim to Prague, you can travel comfortably and safely with FlixBus, BlaBlaCar Bus.
What are the departure and arrival stations when taking the bus from Mannheim to Prague?
Buses travelling between Mannheim and Prague leave from ZOB or Mannheim Hauptbahnhof and arrive at PRG Airport, Florenc, Tomíčkova.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Mannheim to Prague was searched and found on 23 Nov 2025 with a price of R 646To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Mannheim to Prague as early as possible.
You can expect to pay from R 646 to R 1 460 for a bus ticket from Mannheim to Prague based on the last 2 days. You can expect to find the cheapest price for the trip at R 646, which is on 2025-11-23.
