Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Heinrich-von-Stephan-Straße 4-6 | Prague (Central Bus Station Florenc) | Cheapest | ||||
| Bus | Heinrich-von-Stephan-Straße 4-6 | Prague (Na Knížecí) | Fastest |
Last refresh of the prices: Last Saturday at 09:41 CET.
Compare 3 ways to travel from Mannheim to Prague
Among the sustainable travel choices, the carpool stands out as a good way to reach Prague. The journey takes about 5 hours 10 minutes and with fares starting at just £22, it presents an excellent value for a comfortable ride.
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Where are the popular stops in Mannheim and Prague?
Frequently asked questions about travelling by bus from Mannheim to Prague
What's the distance between Mannheim and Prague by coach?
The journey from Mannheim to Prague by coach covers an approximate distance of 268 miles (432 km).
What is the best way to go from Mannheim to Prague without flying?
You can choose the coach to travel this route. The coach ensures a pleasant travel experience, granting you the opportunity to appreciate the scenery as you make your way to your final stop. You might also find carpooling options to travel between the two cities.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Mannheim to Prague was searched and found on 24 Nov 2025 with a price of £24To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Mannheim to Prague as early as possible.
You can expect to pay from £24 to £65 for a bus ticket from Mannheim to Prague based on the last 2 days. You can expect to find the cheapest price for the trip at £24, which is on 2025-11-24.
