Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Heinrich-von-Stephan-Straße 4-6 | Prague (Central Bus Station Florenc) | Cheapest | ||||
| Bus | Heinrich-von-Stephan-Straße 4-6 | Prague (Na Knížecí) | Fastest | ||||
| Bus | Heinrich-von-Stephan-Straße 4-6 | Prague (Central Bus Station Florenc) | No tags | ||||
| Bus | Heinrich-von-Stephan-Straße 4-6 | Prague (Na Knížecí) | No tags | ||||
| Bus | Heinrich-von-Stephan-Straße 4-6 | PRG Airport | No tags |
Last refresh of the prices: Last Saturday at 9:41 AM CET.
Compare 3 ways to go from Mannheim to Prague
Among the sustainable travel choices, the carpool stands out as a good way to reach Prague. The journey takes about 5 hours 10 minutes, and with fares starting at just $41, it presents an excellent value for a comfortable ride.
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Where are the popular stops in Mannheim and Prague?
Frequently asked questions about travelling from Mannheim to Prague by bus
What is the distance between Mannheim and Prague?
It's about 432 km (268 miles) from Mannheim to Prague.
What are the departure and arrival locations for buses traveling from Mannheim to Prague?
Buses departing from ZOB in Mannheim will take you to PRG Airport in Prague.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Mannheim to Prague was searched and found on Nov 24, 2025 with a price of $44To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Mannheim to Prague, as early as possible.
You can expect to pay from $44 to $119 for a bus ticket from Mannheim to Prague based on the last 2 days. You can expect to find the cheapest price for the trip at $44 which is on 2025-11-24.
