Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | P+R Bouillon | Florenc | CheapestFastest | ||||
 | Bus | Luxembourg | Prague (Central Bus Station Florenc) | No tags | ||||
| Bus | Luxembourg | Prague (Central Bus Station Florenc) | No tags | ||||
| Bus | Luxembourg | Prague (Central Bus Station Florenc) | No tags | ||||
| Bus | Luxembourg | Prague (Central Bus Station Florenc) | No tags |
Last refresh of the prices: Yesterday at 12:30 AM CET.
Get from Luxembourg to Prague
The journey takes about 15 hours 25 minutes, and with fares starting at just R 821, it presents an excellent value for a comfortable ride.
Where are the popular stops in Luxembourg and Prague?
Stops in Luxembourg
- A
Luxembourg
3 Rue Genistre, 1623 Luxembourg, Luxembourg - B
Luxembourg Central Station
Place de la Gare 13, 1616 Luxembourg - C
Luxembourg Kirchberg
Rue Alphonse Weicker 4, 2721 Luxemburg, Luxemburg - D
Rue du Commerce
Rue du Commerce, 1351 Luxembourg, Luxembourg
Stops in Prague
- AAviatická, 161 08, Praha 6, Czechia
- BKřižíkova 2b, Nové Město, 186 00 Praha-Praha 8, Czech Republic
- C
Zličín
Drahoňovského, 163 00 Praha 17, Czech Republic - DTomíčkova 2234, Chodov, 148 00 Praha-Praha 11, Czechia
- EChlumecká, 198 00 Praha 20, Czech Republic
- F300/8 Wilsonova, 110 00 Praha, Czechia
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Frequently asked questions about travelling from Luxembourg to Prague by bus
Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.
How much is the bus ticket from Luxembourg to Prague?
The cheapest bus tickets from Luxembourg to Prague start at R 821. The average price for this route is around R 1 413. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the bus journey from Luxembourg to Prague?
The average bus journey time from Luxembourg to Prague is 15h 25m, covering a distance of 600 km. The fastest bus gets you there in 8h 55m and is operated by RegioJet.
Which bus companies service the Luxembourg to Prague route?
Several major bus companies operate on this route with 8 buses available per day, including services from FlixBus, RegioJet, BlaBlaCar Bus.
What is the earliest and latest departure time for the bus from Luxembourg to Prague?
The earliest bus departs from Luxembourg to Prague at 01:00. And the latest bus departs at 23:25.
What are the CO₂ emissions for the bus trip from Luxembourg to Prague?
A bus trip from Luxembourg to Prague produces an estimated 15 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.
What is the best bus company from Luxembourg to Prague?
According to Busbud customers, the highest-rated bus company on this route is RegioJet, with an average rating of 4.1 out of 5 stars based on 1062 reviews.
Which bus company has the best Wi-Fi from Luxembourg to Prague?
Based on reviews on Busbud, the bus company RegioJet has the best Wi-Fi rating with a score of 3.8.
Which bus company offers the most punctual service from Luxembourg to Prague?
According to Busbud traveller reviews, the most punctual bus company on this route is RegioJet, with a punctuality rating of 4.0 out of 5 stars.
Which bus company has the cleanest buses from Luxembourg to Prague?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is RegioJet, with a cleanliness rating of 4.4 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Luxembourg to Prague was searched and found on 08 Jan 2026 with a price of R 699To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Luxembourg to Prague as early as possible.
You can expect to pay from R 699 to R 1 240 for a bus ticket from Luxembourg to Prague based on the last 2 days. You can expect to find the cheapest price for the trip at R 699, which is on 2026-01-08.
Usually FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
