Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Luxembourg | Florenc | CheapestFastest | ||||
 | Bus | Luxembourg | Prague (Central Bus Station Florenc) | No tags | ||||
| Bus | Luxembourg | Prague (Central Bus Station Florenc) | No tags | ||||
| Bus | Luxembourg | Prague (Central Bus Station Florenc) | No tags | ||||
| Bus | Luxembourg | Prague (Central Bus Station Florenc) | No tags |
Last refresh of the prices: Last Sunday at 06:52 CET.
Get from Luxembourg to Prague
The journey takes about 15 hours 25 minutes, and with fares starting at just £35, it presents an excellent value for a comfortable ride.
Compare bus companies
Where are the popular stops in Luxembourg and Prague?
Stops in Luxembourg
- A
Luxembourg
3 Rue Genistre, 1623 Luxembourg, Luxembourg - B
Luxembourg Central Station
Place de la Gare 13, 1616 Luxembourg - C
Luxembourg Kirchberg
Rue Alphonse Weicker 4, 2721 Luxemburg, Luxemburg - D
Rue du Commerce
Rue du Commerce, 1351 Luxembourg, Luxembourg
Stops in Prague
- AAviatická, 161 08, Praha 6, Czechia
- BKřižíkova 2b, Nové Město, 186 00 Praha-Praha 8, Czech Republic
- C
Zličín
Drahoňovského, 163 00 Praha 17, Czech Republic - DTomíčkova 2234, Chodov, 148 00 Praha-Praha 11, Czechia
- EChlumecká, 198 00 Praha 20, Czech Republic
- F300/8 Wilsonova, 110 00 Praha, Czechia
Frequently asked questions about travelling by bus from Luxembourg to Prague
How far is Prague from Luxembourg by coach?
The journey from Luxembourg to Prague by coach covers an approximate distance of 370 miles (597 km).
Is there a way to reach Prague from Luxembourg without flying?
To travel from Luxembourg to Prague without flying, you can take the coaches. Choosing the coach guarantees a comfortable and sustainable travel experience, allowing you to admire the views on your way to your destination. You might also find carpooling options to travel between the two cities.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Luxembourg to Prague was searched and found on 19 Nov 2025 with a price of £33To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Luxembourg to Prague as early as possible.
You can expect to pay from £33 to £113 for a bus ticket from Luxembourg to Prague based on the last 2 days. You can expect to find the cheapest price for the trip at £35, which is on 2025-11-21.
