Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Luxembourg | Florenc | CheapestFastest | ||||
 | Bus | Luxembourg | Prague (Central Bus Station Florenc) | No tags | ||||
| Bus | Luxembourg | Prague (Central Bus Station Florenc) | No tags | ||||
| Bus | Luxembourg | Prague (Central Bus Station Florenc) | No tags | ||||
| Bus | Luxembourg | Prague (Central Bus Station Florenc) | No tags |
Last refresh of the prices: Last Sunday at 6:52 AM CET.
Get from Luxembourg to Prague
This route is served by bus only
The journey takes about 15 hours 25 minutes, and with fares starting at just $64, it presents an excellent value for a comfortable ride.
7bus per day
15h 25mAverage Duration
598 kmDistance
15kgCO₂ emissions
Compare bus companies
3.5 out of 5 stars3.5/511,380 reviews
4 out of 5 stars4/51,057 reviews
3.5 out of 5 stars3.5/511,143 reviews
CZ Bus Companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Rede Expressos, Trenitalia
Where are the popular stops in Luxembourg and Prague?
Stops in Luxembourg
Stops in Prague
Frequently asked questions about travelling from Luxembourg to Prague by bus
What is the travel distance from Luxembourg to Prague?
Luxembourg and Prague are 597 km (370 miles) apart.
What are the departure and arrival locations for buses traveling from Luxembourg to Prague?
Buses departing from Luxembourg in Luxembourg will take you to PRG Airport in Prague.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11-18
No data
11-19
$61
Today
$69
11-21
$64
11-22
No data
11-23
$68
11-24
No data
11-25
No data
The cheapest trip from Luxembourg to Prague was searched and found on Nov 19, 2025 with a price of $61To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Luxembourg to Prague, as early as possible.
You can expect to pay from $61 to $208 for a bus ticket from Luxembourg to Prague based on the last 2 days. You can expect to find the cheapest price for the trip at $64 which is on 2025-11-21.
Top travelled bus routes
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