Next departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | La Serena (Bus terminal La Serena) | Talca (Cruce Varoli) | CheapestFastest | |||||
Andimar + Flixbus Chile | La Serena (Bus terminal La Serena) | Talca (Cruce Varoli) | No tags | |||||
| La Serena (Bus terminal La Serena) | Talca (Cruce Varoli) | No tags | |||||
Andimar + Flixbus Chile | La Serena (Bus terminal La Serena) | Talca (Cruce Varoli) | No tags | |||||
| La Serena (Bus terminal La Serena) | Talca (Cruce Varoli) | No tags |
Last refresh of the prices: Today at 12:09 AM -03.
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Get from La Serena to Talca
The journey takes about 10 hours 50 minutes, and with fares starting at just R 311, it presents an excellent value for a comfortable ride.
Bus La Serena, CL to Talca: Trip Overview
Compare bus companies
Based on 11179 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the Wi-Fi. FlixBus ticket prices on this trip start at R 311
La Serena to Talca Bus
Busbud helps you find a bus from La Serena to Talca. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.
We make it our job to connect you with the most dependable bus companies that cover bus service from La Serena to Talca.
From cheap bus tickets to more luxurious buses travelling from La Serena to Talca, we offer a wide range of bus services to best suit your needs depending on how much your budget is.
Where are the popular stops in La Serena and Talca?
Frequently asked questions on the trip La Serena, CL - Talca
How much does a bus ticket from La Serena to Talca cost?
The bus ticket price from La Serena to Talca starts at R 311. The best way to find cheap bus tickets from La Serena to Talca is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!
How long is the bus ride from La Serena to Talca?
The average travel time between La Serena and Talca is around 10h 50m, although the fastest bus will take about 10h 10m. This is the time it takes to travel the 616 km that separates the two cities.
How many daily bus connections are there between La Serena and Talca?
The number of buses from La Serena to Talca can differ depending on the day of the week. On average, there are 5 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from La Serena to Talca by comparing and selecting the bus that fits your travel style and budget on Busbud.
Which bus companies travel from La Serena to Talca?
When taking the bus from La Serena to Talca, you can travel comfortably and safely with FlixBus.
What are the departure and arrival stations when taking the bus from La Serena to Talca?
Buses travelling between La Serena and Talca leave from Terminal de Buses La Serena or Rotonda La Serena and arrive at Terminal Talca, Parada de Autobus Talca Varoli, Parada de Autobus Talca Cruce Varoli.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from La Serena, CL to Talca was searched and found on 08 Nov 2025 with a price of R 324To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from La Serena, CL to Talca as early as possible.
You can expect to pay from R 324 to R 607 for a bus ticket from La Serena, CL to Talca based on the last 2 days. You can expect to find the cheapest price for the trip at R 324, which is on 2025-11-08.
About Bus Travel
Bus Travel Tips
Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between La Serena and Talca!
From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from La Serena to Talca.
Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from La Serena to Talca that are otherwise impossible to come by with a plane.
Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from La Serena to Talca.
Did you know?
It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.
One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.
Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!
Top travelled bus routes
Why choose Busbud?
The Best Way To Book Bus and Train Tickets
Busbud helps you easily search, compare and book intercity bus tickets on a worlwide scale with our comprehensive list of bus routes and schedules. With several language and currency options available, Busbud seeks to cater to international bus travellers no matter where they are in the world. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.
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Popular Buses Connecting La Serena
Buses Leaving from La Serena
- Bus from La Serena to Coquimbo
- Coach La Serena - Santiago
- Bus La Serena - Temuco
- Bus from La Serena to Ovalle
- Coach La Serena - Antofagasta
- Bus La Serena - Vallenar
- Bus from La Serena to Quillota
- Coach La Serena - Linares
- Bus La Serena - Valparaiso
- Bus from La Serena to Puerto Varas
- Coach La Serena - Iquique
- Bus La Serena - Placilla
- Bus from La Serena to Calama
- Coach La Serena - Pichidangui
- Bus La Serena - Pullalli
Buses Going to La Serena
- Bus from Santiago to La Serena
- Coach Ovalle - La Serena
- Bus Copiapo - La Serena
- Bus from Calama to La Serena
- Coach Temuco - La Serena
- Bus Valparaiso - La Serena
- Bus from Talca to La Serena
- Coach Caldera - La Serena
- Bus Diego de Almagro - La Serena
- Bus from Valdivia to La Serena
- Coach Concon - La Serena
- Bus Vina del Mar - La Serena
- Bus from Villarrica to La Serena
- Coach Iquique - La Serena
- Bus Vallenar - La Serena
Popular Buses Connecting Talca
Buses Leaving from Talca
- Bus from Talca to Cauquenes
- Coach Talca - Concepción
- Bus Talca - Rancagua
- Bus from Talca to San Javier
- Coach Talca - Curico
- Bus Talca - Puerto Montt
- Bus from Talca to Chillan
- Coach Talca - Carahue
- Bus Talca - Santiago
- Bus from Talca to Freire
- Coach Talca - Puerto Varas
- Bus Talca - La Calera
- Bus from Talca to Villarrica
- Coach Talca - Pitrufquén
- Bus Talca - Vina del Mar
Buses Going to Talca
- Bus from Santiago to Talca
- Coach Chillan - Talca
- Bus San Fernando - Talca
- Bus from Rancagua to Talca
- Coach Concepción - Talca
- Bus Constitucion - Talca
- Bus from Copiapo to Talca
- Coach Carahue - Talca
- Bus Parral - Talca
- Bus from Vina del Mar to Talca
- Coach Concon - Talca
- Bus Villarrica - Talca
- Bus from Coquimbo to Talca
- Coach Valparaiso - Talca
- Bus Renaico - Talca