Next departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Terminal de Buses La Serena | Terminal Rodoviario De Iquique, Calle Patricio Lynch #50 | Cheapest | |||||
 | Terminal de Buses La Serena | Terminal Rodoviario De Iquique, Calle Patricio Lynch #50 | Fastest | |||||
| Terminal de Buses La Serena | Terminal Rodoviario De Iquique, Calle Patricio Lynch #50 | No tags | |||||
| Terminal de Buses La Serena | Terminal Rodoviario De Iquique, Calle Patricio Lynch #50 | No tags | |||||
 | Terminal de Buses La Serena | Terminal Rodoviario Iquique | No tags |
Last refresh of the prices: Yesterday at 4:08 PM -03.
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Get from La Serena to Iquique
The journey takes about 18 hours, and with fares starting at just US$27, it presents an excellent value for a comfortable ride.
Bus La Serena, CL to Iquique: Trip Overview
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La Serena to Iquique Bus
Busbud helps you find a bus from La Serena to Iquique. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.
We make it our job to connect you with the most dependable bus companies that cover bus service from La Serena to Iquique.
Whether it is cheap bus tickets or more luxurious buses going to Iquique from La Serena, we help you find what you're looking for based on how much of a budget you have.
Where are the popular stops in La Serena and Iquique?
Frequently asked questions on the trip La Serena, CL - Iquique
How much does a bus ticket from La Serena to Iquique cost?
The bus ticket price from La Serena to Iquique starts at US$27. The best way to find cheap bus tickets from La Serena to Iquique is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!
How long is the bus ride from La Serena to Iquique?
The average travel time between La Serena and Iquique is around 18h, although the fastest bus will take about 17h. This is the time it takes to travel the 1084 km that separates the two cities.
How many daily bus connections are there between La Serena and Iquique?
The number of buses from La Serena to Iquique can differ depending on the day of the week. On average, there are 11 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from La Serena to Iquique by comparing and selecting the bus that fits your travel style and budget on Busbud.
Which bus companies travel from La Serena to Iquique?
When taking the bus from La Serena to Iquique, you can travel comfortably and safely with Pullman San Andres, Pluss Chile, Cikbus Elité.
What are the departure and arrival stations when taking the bus from La Serena to Iquique?
Buses travelling between La Serena and Iquique leave from Terminal de Buses La Serena or Rotonda La Serena and arrive at Patricio Lynch 60, Guatacondo 3430, Eleuterio Ramirez 594.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from La Serena, CL to Iquique was searched and found on 04 Nov 2025 with a price of US$26To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from La Serena, CL to Iquique as early as possible.
You can expect to pay from US$26 to US$61 for a bus ticket from La Serena, CL to Iquique based on the last 2 days. You can expect to find the cheapest price for the trip at US$26, which is on 2025-11-04.
Usually Pullman San Andres, Pluss Chile will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
About Bus Travel
Bus Travel Tips
Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between La Serena and Iquique!
From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from La Serena to Iquique.
Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from La Serena to Iquique.
Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from La Serena to Iquique.
Did you know?
The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.
The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.
9.2% of ground transportation in Europe is done by bus versus 7.4% by train.
Top travelled bus routes
Why choose Busbud?
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Busbud helps you easily search, compare and book intercity bus tickets on a worlwide scale with our comprehensive list of bus routes and schedules. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.
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Popular Buses Connecting La Serena
Buses Leaving from La Serena
- Bus from La Serena to Coquimbo
- Coach La Serena - Santiago
- Bus La Serena - Temuco
- Bus from La Serena to Ovalle
- Coach La Serena - Antofagasta
- Bus La Serena - Vallenar
- Bus from La Serena to Quillota
- Coach La Serena - Linares
- Bus La Serena - Valparaiso
- Bus from La Serena to Puerto Varas
- Coach La Serena - Iquique
- Bus La Serena - Placilla
- Bus from La Serena to Calama
- Coach La Serena - Pichidangui
- Bus La Serena - Pullalli
Buses Going to La Serena
- Bus from Santiago to La Serena
- Coach Ovalle - La Serena
- Bus Copiapo - La Serena
- Bus from Calama to La Serena
- Coach Temuco - La Serena
- Bus Valparaiso - La Serena
- Bus from Talca to La Serena
- Coach Caldera - La Serena
- Bus Diego de Almagro - La Serena
- Bus from Valdivia to La Serena
- Coach Concon - La Serena
- Bus Vina del Mar - La Serena
- Bus from Villarrica to La Serena
- Coach Iquique - La Serena
- Bus Vallenar - La Serena
Popular Buses Connecting Iquique
Buses Leaving from Iquique
- Bus from Iquique to Antofagasta
- Coach Iquique - Santiago
- Bus Iquique - Calama
- Bus from Iquique to Alto Hospicio
- Coach Iquique - Cochabamba
- Bus Iquique - Puerto Montt
- Bus from Iquique to Tocopilla
- Coach Iquique - Los Vilos
- Bus Iquique - Vallenar
- Bus from Iquique to Sierra Gorda
- Coach Iquique - Quillota
- Bus Iquique - Valdivia
- Bus from Iquique to Pichidangui
- Coach Iquique - Caldera
- Bus Iquique - Copiapo
Buses Going to Iquique
- Bus from Santiago to Iquique
- Coach Calama - Iquique
- Bus Copiapo - Iquique
- Bus from La Paz to Iquique
- Coach Coquimbo - Iquique
- Bus Temuco - Iquique
- Bus from Llaillay to Iquique
- Coach Vina del Mar - Iquique
- Bus Taltal - Iquique
- Bus from Antofagasta to Iquique
- Coach Valdivia - Iquique
- Bus Sierra Gorda - Iquique
- Bus from Arica Province to Iquique
- Coach Puerto Montt - Iquique
- Bus Tocopilla - Iquique