Previously seen journeys
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Knoxville Bus Station | Tupelo (Brothers Quick Stop) | No tags | |||||
| Knoxville Bus Station | Tupelo (Brothers Quick Stop) | No tags | |||||
| Knoxville Bus Station | Tupelo (Brothers Quick Stop) | No tags | |||||
| Knoxville Bus Station | Tupelo (Brothers Quick Stop) | No tags | |||||
| Knoxville Bus Station | Tupelo (Brothers Quick Stop) | No tags |
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Get from Knoxville to Tupelo
The journey takes about 11 hours, and with fares starting at just R 2 239, it presents an excellent value for a comfortable ride.
Bus Knoxville, TN to Tupelo: Trip Overview
Compare bus companies
Based on 87349 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the Wi-Fi. Greyhound ticket prices on this trip start at R 2 239
Greyhound Knoxville Tupelo recent customer reviews
My experience was very good. The staff was very helpful and the bus picked me up on time and I arrived on time, so I am very greatful.
Kristopher L.
Knoxville to Tupelo Bus
Busbud helps you find a bus from Knoxville to Tupelo. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.
We make it our job to connect you with the most dependable bus companies that cover bus service from Knoxville to Tupelo.
Discover how much the bus trip from Knoxville to Tupelo will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.
Frequently asked questions on the trip Knoxville, TN - Tupelo
How much does a bus ticket from Knoxville to Tupelo cost?
The bus ticket price from Knoxville to Tupelo starts at R 2 239. The best way to find cheap bus tickets from Knoxville to Tupelo is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!
How long is the bus ride from Knoxville to Tupelo?
The average travel time between Knoxville and Tupelo is around 11h, although the fastest bus will take about 11h. This is the time it takes to travel the 473 km that separates the two cities.
How many daily bus connections are there between Knoxville and Tupelo?
The number of buses from Knoxville to Tupelo can differ depending on the day of the week. On average, there are 1 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Knoxville to Tupelo by comparing and selecting the bus that fits your travel style and budget on Busbud.
Which bus companies travel from Knoxville to Tupelo?
When taking the bus from Knoxville to Tupelo, you can travel comfortably and safely with Greyhound.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Knoxville, TN to Tupelo was searched and found on 01 Nov 2025 with a price of R 2 360To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Knoxville, TN to Tupelo as early as possible.
About Bus Travel
Bus Travel Tips
Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Knoxville and Tupelo!
From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Knoxville to Tupelo.
Buses have the smallest carbon footprint of all motorized transport modes. A bus going from Knoxville to Tupelo will emit half the CO2 emitted by a train, and radically less than a car or an airplane.
Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Knoxville to Tupelo.
Did you know?
It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.
The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.
Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.
Top travelled bus routes
Why choose Busbud?
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Busbud makes bus travel easy. We help travellers find a bus, plot routes, and book intercity bus tickets all over the world. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.
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Popular Buses Connecting Knoxville
Buses Leaving from Knoxville
- Bus from Knoxville to Marathon
- Coach Knoxville - Charlotte
- Bus Knoxville - Lexington
- Bus from Knoxville to Chicago
- Coach Knoxville - Orlando
- Bus Knoxville - Greenville
- Bus from Knoxville to Allentown
- Coach Knoxville - Cleveland
- Bus Knoxville - Dayton
- Bus from Knoxville to Tupelo
- Coach Knoxville - Binghamton
- Bus Knoxville - Florence
- Bus from Knoxville to Colorado Springs
- Coach Knoxville - Holbrook
- Bus Knoxville - Lafayette
Buses Going to Knoxville
- Bus from Nashville to Knoxville
- Coach Memphis - Knoxville
- Bus Charlotte - Knoxville
- Bus from Chicago to Knoxville
- Coach Tampa - Knoxville
- Bus Detroit - Knoxville
- Bus from Plant City to Knoxville
- Coach Savannah - Knoxville
- Bus Laramie - Knoxville
- Bus from Sebring to Knoxville
- Coach Naperville - Knoxville
- Bus Marietta - Knoxville
- Bus from Cortland to Knoxville
- Coach Lufkin - Knoxville
- Bus Grand Rapids - Knoxville
Popular Buses Connecting Tupelo
Buses Leaving from Tupelo
- Bus from Tupelo to Gainesville
- Coach Tupelo - Milwaukee
- Bus Tupelo - Memphis
- Bus from Tupelo to Asheville
- Coach Tupelo - Sacramento
- Bus Tupelo - Grand Rapids
- Bus from Tupelo to San Diego
- Coach Tupelo - Roanoke
- Bus Tupelo - Carbondale
- Bus from Tupelo to El Paso
- Coach Tupelo - Rockledge
- Bus Tupelo - Albuquerque
- Bus from Tupelo to Forrest City
- Coach Tupelo - Gonzales
- Bus Tupelo - Washington
Buses Going to Tupelo
- Bus from Nashville to Tupelo
- Coach Baton Rouge - Tupelo
- Bus New Brunswick - Tupelo
- Bus from Bryant to Tupelo
- Coach Gainesville - Tupelo
- Bus Brunswick - Tupelo
- Bus from Las Vegas to Tupelo
- Coach Marshall - Tupelo
- Bus Moline - Tupelo
- Bus from Albany to Tupelo
- Coach Colorado Springs - Tupelo
- Bus Port Saint Lucie - Tupelo
- Bus from Lake City to Tupelo
- Coach Carbondale - Tupelo
- Bus Columbia - Tupelo
Popular routes in this country
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- Coach Houston - Brownsville
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