Find coaches from Knoxville, TN to Tupelo

Previously seen journeys

Next departures from Knoxville to Tupelo on 23 October
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound
Knoxville Bus Station
Tupelo (Brothers Quick Stop)No tags
Greyhound
Knoxville Bus Station
Tupelo (Brothers Quick Stop)No tags
Greyhound
Knoxville Bus Station
Tupelo (Brothers Quick Stop)No tags
Greyhound
Knoxville Bus Station
Tupelo (Brothers Quick Stop)No tags
Greyhound
Knoxville Bus Station
Tupelo (Brothers Quick Stop)No tags

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Get from Knoxville to Tupelo

busbud logoThis route is served by bus only

The journey takes about 11 hours, and with fares starting at just US$127, it presents an excellent value for a comfortable ride.

1bus per day
11hAverage duration
298 milesDistance
12kgCO₂ emissions

Bus Knoxville, TN to Tupelo: Trip Overview

Average ticket priceUS$127
Average bus trip duration11h
Number of daily buses1
Earliest bus departure19:25
Distance297 miles

Knoxville to Tupelo Bus

Busbud helps you find a bus from Knoxville to Tupelo. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make it our job to connect you with the most dependable bus companies that cover bus service from Knoxville to Tupelo.

Discover how much the bus trip from Knoxville to Tupelo will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip Knoxville, TN - Tupelo

  1. What's the distance between Knoxville and Tupelo by coach?

    The journey from Knoxville to Tupelo by coach covers an approximate distance of 294 miles (473 km).

  2. How can I travel from Knoxville to Tupelo avoiding air travel?

    To travel from Knoxville to Tupelo without flying, you can take the coaches. Choosing the coach guarantees a comfortable and sustainable travel experience, allowing you to admire the views on your way to your destination. You also have the option of utilising carpooling services.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
21/10
US$119
22/10
No data
Today
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24/10
No data
25/10
No data
26/10
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27/10
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28/10
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busbud logoThe cheapest trip from Knoxville, TN to Tupelo was searched and found on 21 Oct 2025 with a price of US$119

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Knoxville, TN to Tupelo as early as possible.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Knoxville and Tupelo!

From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Knoxville to Tupelo.

Buses have the smallest carbon footprint of all motorized transport modes. A bus going from Knoxville to Tupelo will emit half the CO2 emitted by a train, and radically less than a car or an airplane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Knoxville to Tupelo.

Did you know?

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.

Will you be returning to Knoxville, TN by bus?

Bus from Tupelo to Knoxville, TN

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