Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Südseite Hauptbahnhof | PRG Airport | CheapestFastest | ||||
| Bus | Südseite Hauptbahnhof | Prague (Central Bus Station Florenc) | No tags | ||||
| Bus | Südseite Hauptbahnhof | Prague (Central Bus Station Florenc) | No tags | ||||
| Bus | Südseite Hauptbahnhof | Prague (Central Bus Station Florenc) | No tags | ||||
| Bus | Südseite Hauptbahnhof | Prague (Central Bus Station Florenc) | No tags |
Last refresh of the prices: Yesterday at 11:49 AM CET.
Compare 3 ways to travel from Karlsruhe to Prague
Among the sustainable travel choices, the carpool stands out as a good way to reach Prague. The journey takes about 5 hours 10 minutes and with fares starting at just R 495, it presents an excellent value for a comfortable ride.
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Where are the popular stops in Karlsruhe and Prague?
Frequently asked questions about travelling from Karlsruhe to Prague by bus
How much does a bus ticket from Karlsruhe to Prague cost?
The bus ticket price from Karlsruhe to Prague starts at R 523. The best way to find cheap bus tickets from Karlsruhe to Prague is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!
How long is the bus ride from Karlsruhe to Prague?
The average travel time between Karlsruhe and Prague is around 10h 25m, although the fastest bus will take about 7h 45m. This is the time it takes to travel the 453 km that separates the two cities.
How many daily bus connections are there between Karlsruhe and Prague?
The number of buses from Karlsruhe to Prague can differ depending on the day of the week. On average, there are 21 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Karlsruhe to Prague by comparing and selecting the bus that fits your travel style and budget on Busbud.
Which bus companies travel from Karlsruhe to Prague?
When taking the bus from Karlsruhe to Prague, you can travel comfortably and safely with FlixBus, BlaBlaCar Bus, KLR Bus.
What are the departure and arrival stations when taking the bus from Karlsruhe to Prague?
Buses travelling between Karlsruhe and Prague leave from Südseite Hauptbahnhof or Karlsruhe Hbf and arrive at Florenc, Zličín, PRG Airport.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Karlsruhe to Prague was searched and found on 18 Nov 2025 with a price of R 458To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Karlsruhe to Prague as early as possible.
You can expect to pay from R 458 to R 1 303 for a bus ticket from Karlsruhe to Prague based on the last 2 days. You can expect to find the cheapest price for the trip at R 615, which is on 2025-11-21.
