Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Südseite Hauptbahnhof | PRG Airport | CheapestFastest | ||||
| Bus | Südseite Hauptbahnhof | Prague (Central Bus Station Florenc) | No tags | ||||
| Bus | Südseite Hauptbahnhof | Prague (Central Bus Station Florenc) | No tags | ||||
| Bus | Südseite Hauptbahnhof | Prague (Central Bus Station Florenc) | No tags | ||||
| Bus | Südseite Hauptbahnhof | Prague (Central Bus Station Florenc) | No tags |
Last refresh of the prices: Last Monday at 11:49 CET.
Compare 3 ways to travel from Karlsruhe to Prague
Among the sustainable travel choices, the carpool stands out as a good way to reach Prague. The journey takes about 5 hours 10 minutes and with fares starting at just £22, it presents an excellent value for a comfortable ride.
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Where are the popular stops in Karlsruhe and Prague?
Frequently asked questions about travelling by bus from Karlsruhe to Prague
How far is Prague from Karlsruhe by coach?
The journey from Karlsruhe to Prague by coach covers an approximate distance of 281 miles (453 km).
Is there a way to reach Prague from Karlsruhe without flying?
To travel from Karlsruhe to Prague without flying, you can take the coaches. Choosing the coach guarantees a comfortable and sustainable travel experience, allowing you to admire the views on your way to your destination. You might also find carpooling options to travel between the two cities.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Karlsruhe to Prague was searched and found on 18 Nov 2025 with a price of £21To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Karlsruhe to Prague as early as possible.
You can expect to pay from £21 to £58 for a bus ticket from Karlsruhe to Prague based on the last 2 days. You can expect to find the cheapest price for the trip at £22, which is on 2025-11-24.
