Previously seen journeys
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
Greyhound + FlixBus | Bus | Detroit Bus Station | 1116 Woodruff Rd | No tags | ||||
FlixBus + Greyhound | Bus | Detroit Bus Station | 1116 Woodruff Rd | No tags | ||||
 | Bus | Detroit Bus Station | 1116 Woodruff Rd | No tags | ||||
Greyhound + FlixBus | Bus | Detroit Bus Station | 1116 Woodruff Rd | No tags | ||||
| Bus | Detroit Bus Station | 1116 Woodruff Rd | No tags |
Compare 2 ways to travel from Detroit to Greenville
Among the sustainable travel choices, the bus stands out as a good way to reach Greenville. The journey takes about 1 day, 25 minutes and with fares starting at just R 1 610, it presents an excellent value for a comfortable ride.
Where are the popular stops in Detroit and Greenville?
Stops in Greenville
- A
Guadalajara Supermarket Bus Stop
2803 White Horse Rd, Greenville, SC 29611 - B
Greenville Bus Station
9 Hendrix DR, Greenville, SC 29607
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Frequently asked questions about travelling from Detroit, MI to Greenville, SC by bus
How much does a bus ticket from Detroit to Greenville cost?
The bus ticket price from Detroit to Greenville starts at R 1 610. The best way to find cheap bus tickets from Detroit to Greenville is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!
How long is the bus ride from Detroit to Greenville?
The average travel time between Detroit and Greenville is around 1d , although the fastest bus will take about 18h 20m. This is the time it takes to travel the 835 km that separates the two cities.
How many daily bus connections are there between Detroit and Greenville?
The number of buses from Detroit to Greenville can differ depending on the day of the week. On average, there are 3 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Detroit to Greenville by comparing and selecting the bus that fits your travel style and budget on Busbud.
Which bus companies travel from Detroit to Greenville?
When taking the bus from Detroit to Greenville, you can travel comfortably and safely with Greyhound, Amtrak, FlixBus.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Detroit, MI to Greenville, SC was searched and found on 29 Nov 2025 with a price of R 2 081To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Detroit, MI to Greenville, SC as early as possible.
You can expect to pay from R 2 081 to R 30 647 for a bus ticket from Detroit, MI to Greenville, SC based on the last 2 days. You can expect to find the cheapest price for the trip at R 2 081, which is on 2025-11-29.
What's the cheapest way to go from Detroit, MI to Greenville, SC?
The bus is the cheapest travel choice for this destination
