Next departures to Greenville
One passenger / one way
- This trip is recommended because it is the: Cheapest + FastestDeparture time: 22 June atDeparture city: DetroitDeparture location: Detroit Bus StationArrival time: 23 June atDestination city: GreenvilleDestination location: 1116 Woodruff RdOperated by: Greyhound Lines, Inc.
Vehicle: BusDuration: - Departure time: 22 June atDeparture city: DetroitDeparture location: Amtrak StationArrival time: 24 June atDestination city: GreenvilleDestination location: Greenville StationOperated by: Amtrak
Vehicle: BusDuration: - Departure time: 22 June atDeparture city: DetroitDeparture location: Detroit Bus StationArrival time: 23 June atDestination city: GreenvilleDestination location: 1116 Woodruff RdOperated by: Greyhound Lines, Inc.Vehicle: BusDuration:
- Departure time: 22 June atDeparture city: DetroitDeparture location: Amtrak StationArrival time: 24 June atDestination city: GreenvilleDestination location: Greenville StationOperated by: AmtrakVehicle: BusDuration:
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Compare 2 ways to travel from Detroit to Greenville
Busbud recommends taking the bus from Detroit to GreenvilleAmong the sustainable travel choices, the bus stands out as a good way to reach Greenville. The journey takes about 19 hours 5 minutes and with fares starting at just US$75, it presents an excellent value for a comfortable ride.
Bus Detroit to Greenville: Trip Overview
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Detroit to Greenville Bus
With Busbud, comparing and booking tickets for a bus from Detroit to Greenville is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.
Bus service from Detroit to Greenville will be provided by the most trusted bus companies.
From cheap bus tickets to more luxurious buses travelling from Detroit to Greenville, we offer a wide range of bus services to best suit your needs depending on how much your budget is.
Where are the popular stops in Detroit and Greenville?
Frequently asked questions on the trip Detroit, MI - Greenville, SC
How far is Greenville from Detroit by coach?
The journey from Detroit to Greenville by coach covers an approximate distance of 518 miles (835 km).
What is the best way to go from Detroit to Greenville without flying?
To travel from Detroit to Greenville without flying, you can take the coaches. Choosing the coach guarantees a comfortable and sustainable travel experience, allowing you to admire the views on your way to your destination. You might also find carpooling options to travel between the two cities.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Detroit to Greenville was searched and found on 19 Jun 2025 with a price of US$70To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Detroit to Greenville as early as possible.
You can expect to pay from US$70 to US$1,325 for a bus ticket from Detroit to Greenville based on the last 2 days. You can expect to find the cheapest price for the trip at US$87, which is on 2025-06-24.
Usually Amtrak will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
About Bus Travel
Bus Travel Tips
Meet and talk to locals at the bus stations while travelling from Detroit to Greenville.There is no better way to get inside travel information while exploring a new city than to go straight to its people.
Much more than a mere vehicle taking you from Detroit to Greenville, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.
Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Detroit to Greenville that are otherwise impossible to come by with a plane.
Make a music playlist for your bus ride from Detroit to Greenville, and enjoy the scenery to tunes from your own personal soundtrack.
Did you know?
One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.
The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!
The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.
What's the cheapest way to go from Detroit to Greenville?
The bus is the cheapest travel choice for this destinationTop travelled bus routes
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Popular Buses Connecting Detroit
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Popular Buses Connecting Greenville
Buses Leaving from Greenville
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- Coach Greenville - Charlotte
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- Coach Greenville - San Antonio
Buses Going to Greenville
- Bus from Atlanta to Greenville
- Coach Burlington - Greenville
- Bus Nashville - Greenville
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- Coach Charlotte - Greenville
- Bus Memphis - Greenville
- New York - Greenville
- Bus from Myrtle Beach to Greenville
- Coach Kinston - Greenville
- Bus Durham - Greenville
- Washington - Greenville
- Bus from Spartanburg to Greenville