Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
Greyhound Lines, Inc. + FlixBus | Bus | Downtown Greyhound Station | Spartanburg | Cheapest | ||||
 | Bus | Downtown Greyhound Station | Spartanburg | Fastest | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Downtown Greyhound Station | Spartanburg | No tags | ||||
| Bus | Downtown Greyhound Station | Spartanburg | No tags | ||||
FlixBus + Greyhound Lines, Inc. | Bus | Downtown Greyhound Station | Spartanburg | No tags |
Last refresh of the prices: Today at 11:07 AM CST.
Compare 2 ways to travel from Chicago to Spartanburg
Among the sustainable travel choices, the bus stands out as a good way to reach Spartanburg. The journey takes about 1 day, 2 hours and with fares starting at just R 1 933, it presents an excellent value for a comfortable ride.
Compare bus companies
Where are the popular stops in Chicago and Spartanburg?
Frequently asked questions about travelling from Chicago to Spartanburg by bus
How much does a bus ticket from Chicago to Spartanburg cost?
The bus ticket price from Chicago to Spartanburg starts at R 1 933. The best way to find cheap bus tickets from Chicago to Spartanburg is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!
How long is the bus ride from Chicago to Spartanburg?
The average travel time between Chicago and Spartanburg is around 1d 2h, although the fastest bus will take about 19h 25m. This is the time it takes to travel the 916 km that separates the two cities.
How many daily bus connections are there between Chicago and Spartanburg?
The number of buses from Chicago to Spartanburg can differ depending on the day of the week. On average, there are 9 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Chicago to Spartanburg by comparing and selecting the bus that fits your travel style and budget on Busbud.
Which bus companies travel from Chicago to Spartanburg?
When taking the bus from Chicago to Spartanburg, you can travel comfortably and safely with Greyhound, FlixBus.
What are the departure and arrival stations when taking the bus from Chicago to Spartanburg?
Buses travelling between Chicago and Spartanburg leave from Downtown Greyhound Station or Chicago O'Hare International Airport and arrive at Super Acapulco, Spartanburg Bus Stop, Sparta Passenger Center.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Chicago to Spartanburg was searched and found on 20 Nov 2025 with a price of R 2 960To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Chicago to Spartanburg as early as possible.
You can expect to pay from R 2 960 to R 3 753 for a bus ticket from Chicago to Spartanburg based on the last 2 days. You can expect to find the cheapest price for the trip at R 2 960, which is on 2025-11-20.
What's the cheapest way to go from Chicago to Spartanburg?
The bus is the cheapest travel choice for this destination
