Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Estación Terminal de Ómnibius, Santa Fe | Terminal San Luis | Cheapest | ||||
 | Bus | Estación Terminal de Ómnibius, Santa Fe | Terminal San Luis | Fastest | ||||
| Bus | Estación Terminal de Ómnibius, Santa Fe | Terminal San Luis | No tags |
Last refresh of the prices: Today at 08:45 -03.
Get from Santa Fe to San Luis
The journey takes about 10 hours 55 minutes, and with fares starting at just £30, it presents an excellent value for a comfortable ride.
Where are the popular stops in Santa Fe and San Luis?
Stops in Santa Fe
- A
Estación Terminal de Ómnibius, Santa Fe
Estación Terminal de Onmibus Belgrano 2900 , S3000GCH Santa Fe, Argentina
Stops in San Luis
- A
Estación de Interconexión Regional de Ómnibus de San Luis
Avenida del Fundador, s/n, 5700 San Luis - BTerminal de San Luis, Av. del Fundador y Av. Santos Ortiz
Compare bus companies
Frequently asked questions about travelling by bus from Santa Fe, AR to San Luis, AR
Please note that timetables, routes, or operator details shown here may be updated or vary at the time of your journey.
How much is the bus ticket from Santa Fe to San Luis?
The cheapest coach tickets from Santa Fe to San Luis start from £30. The average price for this route is around £36. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus journey from Santa Fe to San Luis?
The average bus journey time from Santa Fe to San Luis is 10h 55m, covering a distance of 345 miles. The fastest bus can take you there in 10h 50m and is operated by Andesmar.
Which bus companies service the Santa Fe to San Luis route?
Several major bus companies operate on this route with 3 buses available per day, including services from 20 de Junio, Andesmar, Flechabus, Tramat.
What is the earliest and latest departure time for the bus from Santa Fe to San Luis?
The earliest bus departs from Santa Fe to San Luis at 02:00. And the latest bus departs at 21:00.
What are the CO₂ emissions for the bus trip from Santa Fe to San Luis?
A bus journey from Santa Fe to San Luis produces an estimated 14 kg of CO₂, making it a highly eco-friendly choice and a mode of travel recommended by Busbud.
Which is the best bus company from Santa Fe to San Luis?
According to Busbud customers, the highest-rated bus company on this route is 20 de Junio, with an average rating of 4.0 out of 5 stars based on 588 reviews.
Which company has the best Wi-Fi from Santa Fe to San Luis?
Based on Busbud reviews, the bus company 20 de Junio has the best Wi-Fi rating with a score of 2.3.
Which bus company offers the most punctual service from Santa Fe to San Luis?
According to Busbud traveller reviews, the most punctual bus company on this route is 20 de Junio, with a punctuality rating of 4.1 out of 5 stars.
Which bus company has the cleanest buses from Santa Fe to San Luis?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is 20 de Junio, with a cleanliness rating of 4.5 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Santa Fe, AR to San Luis, AR was searched and found on 22 Dec 2025 with a price of £33To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Santa Fe, AR to San Luis, AR as early as possible.
